Autor según el artículo: Badia-Cebada L; Peñafiel J; López-Contreras J; Pomar V; Martínez JA; Santana G; Cuquet J; Montero MM; Hidalgo-López C; Andrés M; Gimenez M; Quesada MD; Vaqué M; Iftimie S; Gudiol C; Pérez R; Coloma A; Marron A; Barrufet P; Marimon M; Lérida A; Clarós M; Ramírez-Hidalgo MF; Garcia Pardo G; Martinez MJ; Chamarro EL; Jiménez-Martínez E; Hornero A; Limón E; López M; Calbo E; Pujol M; Gasch O
Departamento: Medicina i Cirurgia
Autor/es de la URV: Iftimie Iftimie, Simona Mihaela
Palabras clave: Risk-factors Mortality Intervention programme Intervention program Healthcare-associated infection Catheter-related bloodstream infections Catheter-related bloodstream infection surveillance prevention multimodal intervention microbiology intervention programme impact icu healthcare-associated infection costs catheter-related bloodstream infection care
Resumen: The incidence of catheter-related bloodstream infections (CRBSI) has fallen over the last decade, especially in intensive care units (ICUs).To assess the existence of concomitant trends in outcomes and to analyse the current risk factors for mortality.A multicentre retrospective cohort study was conducted at 24 Catalan hospitals participating in the Surveillance of healthcare associated infections in Catalonia (VINCat). All hospital-acquired CRBSI episodes diagnosed from January 2010 to December 2019 were included. A common protocol including epidemiological, clinical and microbiological data was prospectively completed. Mortality at 30 days after bacteraemia onset was analysed using the Cox regression model.Over the study period, 4,795 episodes of CRBSI were diagnosed. Among them, 75% were acquired in conventional wards and central venous catheters were the most frequently involved (61%). The 30-day mortality rate was 13.8%, presenting a significant downward trend over the study period: from 17.9% in 2010 to 10.6% in 2019 (HR 0.95 [0.92-0.98]). The multivariate analysis identified age (HR 1.03 [1.02-1.04]), femoral catheter (HR 1.78 [1.33-2.38]), medical ward acquisition (HR 2.07 [1.62-2.65] and ICU acquisition (HR 3.45 [2.7-4.41]), S. aureus (HR 1.59 [1.27-1.99]) and Candida sp. (HR 2.19 [1.64-2.94]) as risk factors for mortality while the mortality rate associated with episodes originating in peripheral catheters was significantly lower (HR 0.69 [0.54-0.88]).Mortality associated with CRBSI has fallen in recent years but remains high. Intervention programs should focus especially on ICUs and medical wards, where incidence and mortality rates are highest.Copyright © 2022 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
Áreas temáticas: Saúde coletiva Química Public, environmental & occupational health Odontología Microbiology (medical) Medicine (miscellaneous) Medicina iii Medicina ii Medicina i Interdisciplinar Infectious diseases General medicine Farmacia Engenharias iv Enfermagem Educação física Ciências biológicas iii Ciências biológicas i Ciências agrárias i Biotecnología Biodiversidade
Direcció de correo del autor: simonamihaela.iftime@urv.cat
Identificador del autor: 0000-0003-0714-8414
Fecha de alta del registro: 2024-08-24
Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
Enlace a la fuente original: https://www.journalofhospitalinfection.com/article/S0195-6701(22)00151-7/fulltext#%20
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Journal Of Hospital Infection. 126 70-77
Referencia de l'ítem segons les normes APA: Badia-Cebada L; Peñafiel J; López-Contreras J; Pomar V; Martínez JA; Santana G; Cuquet J; Montero MM; Hidalgo-López C; Andrés M; Gimenez M; Quesada MD (2022). Decreased Mortality among Patients with Catheter-Related Bloodstream Infections at Catalan Hospitals (2010-2019). Journal Of Hospital Infection, 126(), 70-77. DOI: 10.1016/j.jhin.2022.05.009
DOI del artículo: 10.1016/j.jhin.2022.05.009
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2022
Tipo de publicación: Journal Publications