Autor según el artículo: Díaz-López A; Sans JC; Julvez J; Fernandez-Bares S; Llop S; Rebagliato M; Lertxundi N; Santa-Marina L; Guxens M; Sunyer J; Arija V
Departamento: Ciències Mèdiques Bàsiques
Autor/es de la URV: Arija Val, Maria Victoria / Canals Sans, Josefa / Díaz López, Andres
Palabras clave: Y medio ambiente-(environment deficiency age
Resumen: Evidence suggests that iron status may be linked to symptoms of childhood attention deficit/hyperactivity disorder (ADHD), but there is little data available on the relationship between iron status in pregnancy and the risk of developing ADHD. And the data that does exist is inconsistent. Our aim here is to assess the effect of maternal serum ferritin (SF) and haemoglobin (Hb) levels during pregnancy on manifestations of ADHD in children at 7 years of age. This prospective study analysed data from 1204 mother-child pairs from three Spanish cohorts participating in the INMA project. Maternal SF and Hb levels during pregnancy and other mother and child characteristics were collected. The children's ADHD behaviours were reported by their parents using Conners' Parent Rating Scale-Revised Short Form (CPRS-R:S). In the unadjusted regression analysis, maternal SF was positively associated with children's T-scores on the subscales Cognitive problems/Inattention (β: 0.63, 95%CI 0.06-1.19; p = 0.029) and ADHD index (β: 0.72, 95%CI 0.20-1.24; p = 0.007). These associations were not present after multivariate adjustment or stratification by first and second trimester of pregnancy. The Hb levels were not related to any of the CPRS-R:S subscales in unadjusted or multivariate-adjusted models. We observed no association between maternal SF or Hb levels and the risk of ADHD symptomatology (T-score ≥ 65 for CPRS-R:S subscales). Our results suggest that neither maternal SF nor Hb levels during pregnancy are related to ADHD symptoms in 7-year-old children.© 2022. The Author(s).
Áreas temáticas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Odontología Nutrição Multidisciplinary sciences Multidisciplinary Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Letras / linguística Interdisciplinar Geografía Geociências Farmacia Engenharias iv Engenharias iii Engenharias ii Enfermagem Educação física Educação Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Biotecnología Biodiversidade Astronomia / física
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: andres.diaz@urv.cat victoria.arija@urv.cat josefa.canals@urv.cat
Identificador del autor: 0000-0002-7500-5629 0000-0002-1758-0975 0000-0002-6209-9558
Fecha de alta del registro: 2023-02-19
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.nature.com/articles/s41598-022-23432-1
Referencia al articulo segun fuente origial: Scientific Reports. 12 (1): 20762-20762
Referencia de l'ítem segons les normes APA: Díaz-López A; Sans JC; Julvez J; Fernandez-Bares S; Llop S; Rebagliato M; Lertxundi N; Santa-Marina L; Guxens M; Sunyer J; Arija V (2022). Maternal iron status during pregnancy and attention deficit/hyperactivity disorder symptoms in 7-year-old children: a prospective cohort study. Scientific Reports, 12(1), 20762-20762. DOI: 10.1038/s41598-022-23432-1
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI del artículo: 10.1038/s41598-022-23432-1
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2022
Tipo de publicación: Journal Publications