Autor según el artículo: Rodriguez, A.; Moreno, G.; Gomez, J.; Carbonell, R.; Pico-Plana, E.; Benavent Bofill, C.; Sanchez Parrilla, R.; Trefler, S.; Esteve Pitarch, E.; Canadell, L.; Teixido, X.; Claverias, L.; Bodi, M.;HJ23-Covid-19 Working Grp
Departamento: Medicina i Cirurgia
Autor/es de la URV: Bodi Saera, Maria Amparo / Canadell Vilarrasa, Laura / Gómez Alvarez, Josep / Rodríguez Oviedo, Alejandro Hugo / TREFLER CRESPO, SANDRA INES
Palabras clave: Respiratory failure Mectiarlical ventilation Mechanical ventilation Covid-19 Covi d-19
Resumen: Objective: To describe the clinical and respiratory characteristics of a cohort of 43 patients with COVID-19 after an evolutive period of 28 days.Design: A prospective, single-center observational study was carried out.Setting: Intensive care.Patients: Patients admitted due to COVID-19 and respiratory failure.Interventions: None.Variables: Automatic recording was made of demographic variables, severity parameters, laboratory data, assisted ventilation (HFO: high-flow oxygen therapy and IMV: invasive mechanical ventilation), oxygenation (PaO2, PaO2/FiO(2)) and complications. The patients were divided into three groups: survivors (01), deceased (G2) and patients remaining under admission (03). The chi-squared test or Fisher exact test (categorical variables) was used, along with the Mann Whitney U-test or Wilcoxon test for analyzing the differences between medians. Statistical significance was considered for p<0.05.Results: A total of 43 patients were included (G1-28 [65.1%]; G2= 10 [23.3%] and G3=5 [11.6%]), with a mean age of 65 years (range: 52-72), 62% males, APACHE II 18 (15-24), SOFA 6 (4-7). Arterial hypertension (30.2%) and obesity (25.6%) were the most frequent comorbidities. High -flow oxygen therapy was used in 62.7% of the patients, with failure in 85%. In turn, 95% of the patients required IMV and 85% received ventilation in prone decubitus. In the general population, initial PaO2/FiO(2) improved after 7 days (165 [125-210] vs.194 [153-285]; p=0.02), in the same way as in G1 (164 [125-197] vs. 207 [160-294]; p=0.07), but not in G2 (163 [95-197] vs. 135 [85-177]). No bacterial coinfection was observed. The incidence of IMV-associated pneumonia was high (13 episodes/1000 days of IMV).Conclusions: Patients with COVID-19 require early IMV, a high frequency of ventilation in prone decubitus, and have a high incidence of failed HFO. The lack of improvement of PaO2/FiO(2) at 7 days could be a prognostic marker. (C) 2020 Elsevier Espana, S.L.U. y SEMICYUC. All rights reserved.
Áreas temáticas: Medicina iii Medicina ii Medicina i General medicine Educação física Critical care medicine Critical care and intensive care medicine
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: josep.gomez@urv.cat alejandrohugo.rodriguez@urv.cat laura.canadell@urv.cat mariaamparo.bodi@urv.cat mariaamparo.bodi@urv.cat
Identificador del autor: 0000-0002-0573-7621 0000-0001-8828-5984 0000-0001-7652-8379 0000-0001-7652-8379
Fecha de alta del registro: 2024-06-28
Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
Enlace a la fuente original: https://www.sciencedirect.com/science/article/pii/S021056912030190X?via%3Dihub
Referencia al articulo segun fuente origial: Medicina Intensiva. 44 (9): 525-533
Referencia de l'ítem segons les normes APA: Rodriguez, A.; Moreno, G.; Gomez, J.; Carbonell, R.; Pico-Plana, E.; Benavent Bofill, C.; Sanchez Parrilla, R.; Trefler, S.; Esteve Pitarch, E.; Canad (2020). Severe infection due to the SARS-CoV-2 coronavirus: Experience of a tertiary hospital with COVID-19 patients during the 2020 pandemic. Medicina Intensiva, 44(9), 525-533. DOI: 10.1016/j.medin.2020.05.018
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI del artículo: 10.1016/j.medin.2020.05.018
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2020
Tipo de publicación: Journal Publications
Repositori URV