Autor según el artículo: Romero-Aroca, P; Verges, R; Pascual-Fontanilles, J; Valls, A; Franch, J; Barrot, J; Mundet, X; La Torre, A; Moreno, A; Sagarra, R; Basora, J; Garcia-Curto, E; Baget-Bernaldiz, M
Departamento: Enginyeria Informàtica i Matemàtiques
Autor/es de la URV: Baget Bernaldiz, Marc / Moreno Ribas, Antonio / Pascual Fontanilles, Jordi / Romero Aroca, Pedro / Valls Mateu, Aïda / Vergés Pujol, Raquel
Palabras clave: Tc/hdl-cholesterol ratio Statins Risk No-hdl-c/hdl-cholesterol ratio Lipids Fibrates Diabetic retinopathy 2 tc/hdl-cholesterol ratio statins progression prevention no-hdl-c/hdl-cholesterol ratio lipids fibrates disease diagnosis cholesterol
Resumen: (1) Background: Diabetic retinopathy (DR) remains the leading cause of low vision and blindness in young adults of working age. Although the most important risk factors—such as the duration of diabetes mellitus (DM) and glycemic control measured by HbA1c—are known, the effects of lipids are not as clear. The aim of the present study is to analyze the effects of lipids on the development of DR. (2) Methods: This is a retrospective study of a population of 175,645 DM2 patients, during the period 2010 to 2020, in which the effects of different lipid factors are studied. (3) Results: The variables that most influenced the development of DR in our study, based on significance and cumulative hazard (CH), were arterial hypertension (CH 1.217, p < 0.001), HbA1c levels (CH 1.162, p = 0.001), microalbuminuria (CH 1.012, p < 0.001), LDL-C cholesterol (CH 1.007, p = 0.012), TC/HDL-C index (CH 1.092, p < 0.001), No-HDL-C/HDL-C index (CH 1.065, p = 0.002), the use of statins (CH 1.001, p = 0.005), and body mass index (CH 1.007, p < 0.001). (4) Conclusions: LDL-cholesterol, TC/HDL-C, and No-HDL-C/HDL-C indices are related to the development of DR, and there is a protective effect of HDL-cholesterol and the use of fibrates.
Áreas temáticas: Medicine, general & internal Medicine (miscellaneous) Medicine (all)
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: jordi.pascual@urv.cat jordi.pascual@urv.cat marc.baget@urv.cat aida.valls@urv.cat pedro.romero@urv.cat antonio.moreno@urv.cat jordi.pascual@urv.cat raquel.vergesp@estudiants.urv.cat
Identificador del autor: 0000-0002-7528-5819 0000-0002-7528-5819 0000-0003-3616-7809 0000-0002-7061-8987 0000-0003-3945-2314 0000-0002-7528-5819 0000-0003-2693-0612
Fecha de alta del registro: 2024-01-13
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.mdpi.com/2077-0383/12/20/6674
URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Journal Of Clinical Medicine. 12 (20):
Referencia de l'ítem segons les normes APA: Romero-Aroca, P; Verges, R; Pascual-Fontanilles, J; Valls, A; Franch, J; Barrot, J; Mundet, X; La Torre, A; Moreno, A; Sagarra, R; Basora, J; Garcia-C (2023). Effect of Lipids on Diabetic Retinopathy in a Large Cohort of Diabetic Patients after 10 Years of Follow-Up. Journal Of Clinical Medicine, 12(20), -. DOI: 10.3390/jcm12206674
DOI del artículo: 10.3390/jcm12206674
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2023
Tipo de publicación: Journal Publications
Repositori URV