Autor según el artículo: Restrepo-Benavides, M; Lozano-Arce, D; Gonzalez-Garcia, LN; Báez-Aguirre, F; Ariza-Aranguren, G; Faccini, D; Zambrano, MM; Jiménez, P; Fernández-Bravo, A; Restrepo, S; Guevara-Suarez, M
Departamento: Ciències Mèdiques Bàsiques
Autor/es de la URV: Fernández Bravo, Ana
Palabras clave: United-states Toxin Secretion systems Piangua Penaeus-monodon fabricius Parahaemolyticus Oxford nanopore Multidrug resistance Infections Iii secretion systems Identification Host Gridion Effector protein Bivalve Alginolyticus
Resumen: The genus Vibrio includes pathogenic bacteria able to cause disease in humans and aquatic organisms, leading to disease outbreaks and significant economic losses in the fishery industry. Despite much work on Vibrio in several marine organisms, no specific studies have been conducted on Anadara tuberculosa. This is a commercially important bivalve species, known as "piangua hembra," along Colombia's Pacific coast. Therefore, this study aimed to identify and characterize the genomes of Vibrio isolates obtained from A. tuberculosa. Bacterial isolates were obtained from 14 A. tuberculosa specimens collected from two locations along the Colombian Pacific coast, of which 17 strains were identified as Vibrio: V. parahaemolyticus (n = 12), V. alginolyticus (n = 3), V. fluvialis (n = 1), and V. natriegens (n = 1). Whole genome sequence of these isolates was done using Oxford Nanopore Technologies (ONT). The analysis revealed the presence of genes conferring resistance to beta-lactams, tetracyclines, chloramphenicol, and macrolides, indicating potential resistance to these antimicrobial agents. Genes associated with virulence were also found, suggesting the potential pathogenicity of these Vibrio isolates, as well as genes for Type III Secretion Systems (T3SS) and Type VI Secretion Systems (T6SS), which play crucial roles in delivering virulence factors and in interbacterial competition. This study represents the first genomic analysis of bacteria within A. tuberculosa, shedding light on Vibrio genetic factors and contributing to a comprehensive understanding of the pathogenic potential of these Vibrio isolates.
Áreas temáticas: Physiology Microbiology (medical) Microbiology Infectious diseases Immunology and microbiology (miscellaneous) Immunology and microbiology (all) Genetics General medicine General immunology and microbiology Ecology Ciências agrárias i Cell biology
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: ana.fernandez@urv.cat
Identificador del autor: 0000-0001-7637-5958
Fecha de alta del registro: 2024-08-03
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://journals.asm.org/doi/10.1128/spectrum.02928-23
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Microbiology Spectrum. 12 (2): e02928-23-
Referencia de l'ítem segons les normes APA: Restrepo-Benavides, M; Lozano-Arce, D; Gonzalez-Garcia, LN; Báez-Aguirre, F; Ariza-Aranguren, G; Faccini, D; Zambrano, MM; Jiménez, P; Fernández-Bravo (2024). Unveiling potential virulence determinants in Vibrio isolates from Anadara tuberculosa through whole genome analyses. Microbiology Spectrum, 12(2), e02928-23-. DOI: 10.1128/spectrum.02928-23
DOI del artículo: 10.1128/spectrum.02928-23
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2024
Tipo de publicación: Journal Publications