Autor según el artículo: Peiró ÓM; Delgado-Cornejo JR; Sánchez-Giménez R; del-Moral-Ronda V; Lal-Trehan N; Rocamora-Horrach M; Carrasquer A; Peraire J; Fort-Gallifa I; Bardaji A
Departamento: Medicina i Cirurgia
Autor/es de la URV: Bardají Ruiz, Alfredo / Carrasquer Cucarella, Ana Maria / Peiró Ibáñez, Óscar Manuel / Peraire Forner, José Joaquin
Palabras clave: Troponin Sars-cov-2 Prognostic Myocardial injury Covid-19
Resumen: Introduction: The prognostic ability of myocardial injury across different waves of the COVID-19 pandemic is not well established. The purpose of this study was to evaluate the prevalence and prognostic implications of myocardial injury in the first and sixth wave of COVID-19. Methods: We conducted a retrospective observational study that included patients admitted to the emergency department with COVID-19 with data on concentrations of cardiac troponin during the first and sixth wave. We compared the prevalence of myocardial injury and its predictive capacity for 30-day all-cause death in both waves. Results and discussion: A total of 346 patients were included (1st wave 199 and 6th wave 147 patients). The prevalence of myocardial injury was 21% with non-significant differences between waves. Myocardial injury was associated, in both waves, with a higher prevalence of comorbidities and with an increased risk of 30-day all-cause death [1st wave HR: 3.73 (1.84–7.55); p < 0.001 and 6th wave HR: 3.13 (1.23–7.92); p = 0.016], with non-significant differences in predictive capacity between groups after ROC curve analysis [AUC: 1st wave 0.829 (95% CI: 0.764–0.895) and 6th wave 0.794 (95% CI: 0.711–0.876)]. As limitations, this is a retrospective study with a relatively small simple size and troponin assay was performed at the discretion of the emergency physician so selection bias could be present. In conclusion, the prevalence of myocardial injury and its prognostic capacity was similar in both waves despite vaccination programs. Myocardial injury predicts short-term mortality in all COVID-19 patients, so they should be treated intensively.
Áreas temáticas: Cardiology and cardiovascular medicine Cardiac & cardiovascular systems
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: oscarmanuel.peiro@urv.cat anamaria.carrasquer@urv.cat joaquim.peraire@urv.cat alfredo.bardaji@urv.cat anamaria.carrasquer@urv.cat oscarmanuel.peiro@urv.cat
Identificador del autor: 0000-0001-7808-5479 0000-0003-1900-6974
Fecha de alta del registro: 2024-04-06
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.frontiersin.org/articles/10.3389/fcvm.2024.1297824/full
Referencia al articulo segun fuente origial: Front Cardiovasc Med. 11
Referencia de l'ítem segons les normes APA: Peiró ÓM; Delgado-Cornejo JR; Sánchez-Giménez R; del-Moral-Ronda V; Lal-Trehan N; Rocamora-Horrach M; Carrasquer A; Peraire J; Fort-Gallifa I; Bardaji (2024). Prevalence and prognostic implications of myocardial injury across different waves of COVID-19. Front Cardiovasc Med, 11(), -. DOI: 10.3389/fcvm.2024.1297824
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI del artículo: 10.3389/fcvm.2024.1297824
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2024
Tipo de publicación: Journal Publications