Conjunts de dades de producció científicaBioquímica i Biotecnologia

Replication Data for Profiling Bitter Taste Receptors (TAS2R) along the Gastrointestinal Tract and their Influence on Enterohormone Secretion. Gender- and Age-Related Effects in the Colon

  • Dades identificatives

    Identificador:  PC:4441
    Handle: https://hdl.handle.net/20.500.11797/PC4441
    Autors:  Jalsevac, Florijan; Descamps-Solà, Maria; Grau-Bové, Carme; Segú, Helena; Auguet, Teresa; Avilés-Jurado, Francesc Xavier; Balaguer, Francesc; Jorba, Rosa; Beltrán-Debón, Raúl; Blay, Maria Teresa; Terra, Ximena; Pinent, Montserrat; Ardévol, Anna
    Resum:
    This dataset was created for the purpose of analyzing data that was published in the article titled "Profiling Bitter Taste Receptors (TAS2R) along the Gastrointestinal Tract and their Influence on Enterohormone Secretion. Gender- and Age-Related Effects in the Colon". The aim for this dataset was to describe the presence of different bitter taste receptors (TAS2Rs) in different segments of the gastrointestinal tract (GIT), the effect of ageing, location (ascending/descending colon) and sex on the expression of these receptors in the human colon, the expression of these receptors in a cellular study model (HuTu-80 ) and the effect of specific bitter agonists on the secretion of enterohormone GLP-1 in the cellular model. It contains the Ct numbers of the expression of samples in different segments of the GIT, some basic information of the samples obtained from colon for the purpose of identifying their study cohort, the expression Ct numbers of the bitter taste receptors in the cellular model, and the levels of GLP-1 secreted from the cells after stimulation with specific bitter ligands.

  • Altres:

    Tipus de document: info:eu-repo/semantics/other
    DOI: 10.34810/data1647
    Publicacions relacionades: Article Submitted for publication
    Grup de recerca: Molecular Bioactivity of Food- Bioactivitat Molecular dels Aliments
    Departament: Bioquímica i Biotecnologia
    Autor: Jalsevac, Florijan; Descamps-Solà, Maria; Grau-Bové, Carme; Segú, Helena; Auguet, Teresa; Avilés-Jurado, Francesc Xavier; Balaguer, Francesc; Jorba, Rosa; Beltrán-Debón, Raúl; Blay, Maria Teresa; Terra, Ximena; Pinent, Montserrat; Ardévol, Anna
    Data alta repositori: 2025-04-24
    Any de publicació de la dataset: 2024
    Matèria: Medicine, Health and Life Sciences
    Identificador del investigador: 0000-0002-6163-9372; 0009-0009-7400-8578; 0000-0001-5128-9607; 0000-0001-8892-052X; 0000-0003-0396-6428; 0000-0001-5560-8097; 0000-0002-0206-0539; 0000-0003-3307-4340; 0000-0001-9691-1906; 0000-0002-6256-9847; 0000-0003-1043-5844; 0000-0003-3550-5378; 0000-0003-0156-7538
    Idioma: en
    Publicat per (editora): Universitat Rovira i Virgili (URV)
    Drets d'accés: info:eu-repo/semantics/openAccess
    Tipus de dades: Experimental data
    Resum: This dataset was created for the purpose of analyzing data that was published in the article titled "Profiling Bitter Taste Receptors (TAS2R) along the Gastrointestinal Tract and their Influence on Enterohormone Secretion. Gender- and Age-Related Effects in the Colon". The aim for this dataset was to describe the presence of different bitter taste receptors (TAS2Rs) in different segments of the gastrointestinal tract (GIT), the effect of ageing, location (ascending/descending colon) and sex on the expression of these receptors in the human colon, the expression of these receptors in a cellular study model (HuTu-80 ) and the effect of specific bitter agonists on the secretion of enterohormone GLP-1 in the cellular model. It contains the Ct numbers of the expression of samples in different segments of the GIT, some basic information of the samples obtained from colon for the purpose of identifying their study cohort, the expression Ct numbers of the bitter taste receptors in the cellular model, and the levels of GLP-1 secreted from the cells after stimulation with specific bitter ligands.

  • Paraules clau:

    Receptors; Plasma Parameters; Gastrointestinal system
    Medicine
    Health and Life Sciences

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