Conjunts de dades de producció científicaBioquímica i Biotecnologia

Replication Data for Profiling Bitter Taste Receptors (TAS2R) along the Gastrointestinal Tract and their Influence on Enterohormone Secretion. Gender- and Age-Related Effects in the Colon

  • Identification data

    Identifier:  PC:4441
    Handle: https://hdl.handle.net/20.500.11797/PC4441
    Authors:  Jalsevac, Florijan; Descamps-Solà, Maria; Grau-Bové, Carme; Segú, Helena; Auguet, Teresa; Avilés-Jurado, Francesc Xavier; Balaguer, Francesc; Jorba, Rosa; Beltrán-Debón, Raúl; Blay, Maria Teresa; Terra, Ximena; Pinent, Montserrat; Ardévol, Anna
    Abstract:
    This dataset was created for the purpose of analyzing data that was published in the article titled "Profiling Bitter Taste Receptors (TAS2R) along the Gastrointestinal Tract and their Influence on Enterohormone Secretion. Gender- and Age-Related Effects in the Colon". The aim for this dataset was to describe the presence of different bitter taste receptors (TAS2Rs) in different segments of the gastrointestinal tract (GIT), the effect of ageing, location (ascending/descending colon) and sex on the expression of these receptors in the human colon, the expression of these receptors in a cellular study model (HuTu-80 ) and the effect of specific bitter agonists on the secretion of enterohormone GLP-1 in the cellular model. It contains the Ct numbers of the expression of samples in different segments of the GIT, some basic information of the samples obtained from colon for the purpose of identifying their study cohort, the expression Ct numbers of the bitter taste receptors in the cellular model, and the levels of GLP-1 secreted from the cells after stimulation with specific bitter ligands.

  • Others:

    Document type: info:eu-repo/semantics/other
    DOI: 10.34810/data1647
    Related publications: Article Submitted for publication
    Research group: Molecular Bioactivity of Food- Bioactivitat Molecular dels Aliments
    Departament: Bioquímica i Biotecnologia
    Author: Jalsevac, Florijan; Descamps-Solà, Maria; Grau-Bové, Carme; Segú, Helena; Auguet, Teresa; Avilés-Jurado, Francesc Xavier; Balaguer, Francesc; Jorba, Rosa; Beltrán-Debón, Raúl; Blay, Maria Teresa; Terra, Ximena; Pinent, Montserrat; Ardévol, Anna
    Repository ingest date: 2025-04-24
    Dataset publication year: 2024
    Subject matter: Medicine, Health and Life Sciences
    Researcher identifier: 0000-0002-6163-9372; 0009-0009-7400-8578; 0000-0001-5128-9607; 0000-0001-8892-052X; 0000-0003-0396-6428; 0000-0001-5560-8097; 0000-0002-0206-0539; 0000-0003-3307-4340; 0000-0001-9691-1906; 0000-0002-6256-9847; 0000-0003-1043-5844; 0000-0003-3550-5378; 0000-0003-0156-7538
    Language: en
    Published by (editorial): Universitat Rovira i Virgili (URV)
    Access rights: info:eu-repo/semantics/openAccess
    Data type: Experimental data
    Abstract: This dataset was created for the purpose of analyzing data that was published in the article titled "Profiling Bitter Taste Receptors (TAS2R) along the Gastrointestinal Tract and their Influence on Enterohormone Secretion. Gender- and Age-Related Effects in the Colon". The aim for this dataset was to describe the presence of different bitter taste receptors (TAS2Rs) in different segments of the gastrointestinal tract (GIT), the effect of ageing, location (ascending/descending colon) and sex on the expression of these receptors in the human colon, the expression of these receptors in a cellular study model (HuTu-80 ) and the effect of specific bitter agonists on the secretion of enterohormone GLP-1 in the cellular model. It contains the Ct numbers of the expression of samples in different segments of the GIT, some basic information of the samples obtained from colon for the purpose of identifying their study cohort, the expression Ct numbers of the bitter taste receptors in the cellular model, and the levels of GLP-1 secreted from the cells after stimulation with specific bitter ligands.

  • Keywords:

    Receptors; Plasma Parameters; Gastrointestinal system
    Medicine
    Health and Life Sciences

  • Documents:

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