Multímeros de la adiponectina en la diabetes gestacional: relación con parámetros maternos y repercusión en el crecimiento fetal

Identificador:  TDX:1023

Handle: https://hdl.handle.net/20.500.11797/TDX1023

Autors:  Ballesteros Pérez, Mònica

Resum:
Adipose tissue plays an active role in metabolic homeostasis. Its functions are mediated by factors secreted by adipocytes known as adipocytokines. Adiponectin is an adipocytokine produced in the adult fat tissue and fetuses in various fetal tissues. Present in the bloodstream in the form of multimers of different molecular weights with different functional implications. Is inversely related to levels of insulin resistance, which increased during pregnancy, gestational diabetes to worsen in the (DMG), an entity associated with fetal macrosomia, we postulate that the quantity and distribution of adiponectin multimers both maternal and fetal, can be one of the factors involved in regulating fetal growth and neonatal adiposity. We postulate a correlation of levels of maternal and fetal adiponectin. We also evaluated new methods of weight estimation in three-dimensional ultrasound.