Participación del estrés en la generación de puntos gatillo miofasciales

Identificador:  TDX:3230

Handle: https://hdl.handle.net/20.500.11797/TDX3230

Autors:  Bosque Alberich, Marc

Resum:
siguientes y normalizados a la semana. Con el estrés nico, se obtuvo un incremento mayor que se mantuvo durante 15 días. Sin embargo, la técnica de cián no PGM en ninguno de los periodos post-tratamiento estudiados. Conclusión: el estrés, tanto en su forma aguda como nica, es insuficiente para generar PGM actuando como factor aislado, aunque induce algunos de sus signos característicos electrofisiológicos y electromiográficos, convirtiéndose en un elemento relevante en la generación, perpetuación, agravamiento y / o nificación del SDM. Myofascial trigger points (PGM) are caused by a set of sensitive, motor, and autonomic symptoms, and constitute myofascial muscle pain syndrome (SDM). Although there is no evidence, stress has been proposed as a generator and perpetuator of SDM. The most accepted pathophysiological theory proposes that PGMs involve an increase in ACh in the affected muscles. Objective: The aim of this study was to evaluate the relationship between stress and the generation of PGM. Methods: 5 acute stressors (immobilization, forced swimming, food and water deprivation, social isolation, and ultrasound) were analyzed in 4–6-week-old male mice. Subsequently, these stresses were combined to try to generate chronic stress. For the study of ACh release, the muscles of the animals were evaluated before and after the application of stress, using two techniques: spontaneous neurotransmission intracellular recordings (mEPPs) and endplate noise electromyographic recordings. For morphological study, PAS-Alcián technique were performed in order to see PGM.