Tesis doctorals> Departament d'Enginyeria Química

Real-time aptapcr: a novel approach exploiting nucleic acid aptamers for ultrasensitive detection of analytes for clinical diagnostic and in food analysis

  • Identification data

    Identifier: TDX:1059
    Handle: https://hdl.handle.net/20.500.11797/TDX1059
    Authors:
    Pinto, Alessandro
    Abstract:
    The thesis aimed to develop and characterize a novel detection approach, which we termed aptaPCR exploiting nucleic acid aptamers as combined recognition and reporter biocomponents for the ultrasensitive detection of analytes. Nucleic acid aptamers are synthetic ligands selected from vast combinatorial libraries through a process referred to as SELEX – Systematic Evolution of Ligand By Exponential Enrichment. As compared to other natural and synthetic receptor, aptamers possess unique chemical and biochemical characteristics, such as: a well known chemistry, remarkable stability, an ability to be selected against virtually any target even in non-physiological conditions

  • Others:

    Date: 2012-04-19
    Departament/Institute: Departament d'Enginyeria Química Universitat Rovira i Virgili.
    Language: eng
    Identifier: http://hdl.handle.net/10803/80744
    Source: TDX (Tesis Doctorals en Xarxa)
    Author: Pinto, Alessandro
    Director: O'Sullivan, Ciara
    Format: application/pdf 116 p.
    Publisher: Universitat Rovira i Virgili
    Keywords: gliadin Thrombin QPCR aptaPCR Aptamer
    Title: Real-time aptapcr: a novel approach exploiting nucleic acid aptamers for ultrasensitive detection of analytes for clinical diagnostic and in food analysis
    Subject: 577 - Bioquímica. Biologia molecular. Biofísica 543 - Química analítica

  • Keywords:

    577 - Bioquímica. Biologia molecular. Biofísica
    543 - Química analítica

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