Tesis doctorals> Departament d'Enginyeria Química

Real-time aptapcr: a novel approach exploiting nucleic acid aptamers for ultrasensitive detection of analytes for clinical diagnostic and in food analysis

  • Datos identificativos

    Identificador: TDX:1059
    Autores:
    Pinto, Alessandro
    Resumen:
    The thesis aimed to develop and characterize a novel detection approach, which we termed aptaPCR exploiting nucleic acid aptamers as combined recognition and reporter biocomponents for the ultrasensitive detection of analytes. Nucleic acid aptamers are synthetic ligands selected from vast combinatorial libraries through a process referred to as SELEX – Systematic Evolution of Ligand By Exponential Enrichment. As compared to other natural and synthetic receptor, aptamers possess unique chemical and biochemical characteristics, such as: a well known chemistry, remarkable stability, an ability to be selected against virtually any target even in non-physiological conditions
  • Otros:

    Fecha: 2012-04-19
    Departamento/Instituto: Departament d'Enginyeria Química Universitat Rovira i Virgili.
    Idioma: eng
    Identificador: http://hdl.handle.net/10803/80744
    Fuente: TDX (Tesis Doctorals en Xarxa)
    Autor: Pinto, Alessandro
    Director: O'Sullivan, Ciara
    Formato: application/pdf 116 p.
    Editor: Universitat Rovira i Virgili
    Palabra clave: gliadin Thrombin QPCR aptaPCR Aptamer
    Título: Real-time aptapcr: a novel approach exploiting nucleic acid aptamers for ultrasensitive detection of analytes for clinical diagnostic and in food analysis
    Materia: 577 - Bioquímica. Biologia molecular. Biofísica 543 - Química analítica
  • Palabras clave:

    577 - Bioquímica. Biologia molecular. Biofísica
    543 - Química analítica
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