Gold catalysis: Total Synthesis of the Englerins and an Approach Towards Shisanwilsonene A

Tesis doctorals> Departament de Química

Gold catalysis: Total Synthesis of the Englerins and an Approach Towards Shisanwilsonene A

Identification data

Identifier: TDX:1238

Handle: https://hdl.handle.net/20.500.11797/TDX1238

Authors:
Delpont, Nicolas

Abstract:
Over the last years, our research group reported several methodologies dealing with the activation of alkynes using gold as a catalyst. One of the objectives of this Thesis was the development of a new catalytic system for the intramolecular [4+2] cycloaddition of aryl enynes. After screening of different ligands and several optimizations, up to 88% ee could be obtained by using a bulky chiral gold phosphite. The two other chapters of this Thesis are dealing with the synthesis of natural products involving a gold-catalyzed transformation as a key step in the synthesis. The total synthesis of (-)-englerins A and B is reported and a study towards the synthesis of Schisanwilsonene A is also described.
Others:

Date: 2011-04-26
Departament/Institute: Departament de Química Analítica i Química Orgànica Universitat Rovira i Virgili.
Language: eng
Identifier: http://hdl.handle.net/10803/124043
Source: TDX (Tesis Doctorals en Xarxa)
Author: Delpont, Nicolas
Director: Echavarren, Antonio M.
Format: application/pdf 285 p.
Publisher: Universitat Rovira i Virgili
Keywords: Gold Catalysis and Synthesis
Title: Gold catalysis: Total Synthesis of the Englerins and an Approach Towards Shisanwilsonene A
Subject: 547 - Química orgànica 54 - Química

Keywords:

547 - Química orgànica
54 - Química
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