Epidemiología de la enfermedad cerebrovascular isquémica en mayores de 60 años del área de Tarragona: datos del estudio CAPAMIS

Identifier:  TDX:2929

Handle: https://hdl.handle.net/20.500.11797/TDX2929

Authors:  Satuè Gracia, Eva María

Abstract:
Background. Stroke is an important cause of mortality and the number of stroke survivors is also increasing. Their approach and follow-up are a priority in health policy. This study provides rigorous and up-to-date data, including incidences in specific population subgroups, of our territory that will allow a better knowledge and management of the disease. Methods. Population based cohort study. It included 27,204 patients ≥ 60 years of the region of Tarragona, followed during 36 months. Demographic variables, risk factors and basal comorbidities were registered from primary care computerized clinical records (e-cap). Hospital discharge reports with ischemic stroke diagnosis were reviewed; global and by subgroups of patients incidence rates (per 100,000 persons-year) were calculated, as well as lethality rates. The association between basal characteristics and time to first event was estimated using Cox regression models. Results. The overall incidence was 435 / 100,000 persons-year. Basal conditions significantly and independently associated with an increased risk of ischemic stroke were: previous stroke, atrial fibrillation, ischemic heart disease, active smoking, diabetes and age. The case-fatality rate was 13.1% and increased with age, reaching 21% in the group of 80 or more years. Discussion. The incidence and lethality of ischemic stroke in our territory can be considered medium referred to Spain and low referred to the whole of Europe. The history of arteriosclerotic disease (especially previous stroke) and atrial fibrillation are the main risk factors in this age group.