Factors prenatals i perinatals relacionats amb el desenvolupament cognitiu i problemes psicològics en l'infant

Identifier:  TDX:2974

Handle: https://hdl.handle.net/20.500.11797/TDX2974

Authors:  Roigé Castellví, Joana

Abstract:
Pregnancy is a period of maximum vulnerability due to the influence of multiple risk factors which can originate multiple developmental problems, diseases and pathologies throughout the life of person. Multiple risk factors related to child neurodevelopment have been described. Two of them are maternal nutritional status and prenatal smoke exposure. The main objective of this thesis is to investigate the prenatal and perinatal risk factors (specifically the levels of preconceptional homocysteine and prenatal smoke exposure) involved in the neuropsychological development of the child. In addition, we also want to study the influence of environmental risk factors on the diagnosis of ADHD, as well as analyze the validity of Conners 3 AI and the specific scales of CBCL / 6-18 and YSR711-18 for the ADHD screening. In order to highlight the aim of this thesis, we considered the results obtained from three different studies: the PreC study, the NutCir study (both are birth cohort studies with a prospective longitudinal design) and the EPINED study (double-phase cross-sectional study). From the results obtained we can conclude that the prenatal period is a period of great importance for the neurodevelopment of the child in the long term. Specifically, the results have allowed us to corroborate that the nutritional status of the mother prior to conception and prenatal smoke exposure are risk factors for neurodevelopmental problems in the long term.