Increasing of secondary cobalamin deficiencies in newborns in Catalonia in the last eight years

Identifier:  TFG:5939

Handle: https://hdl.handle.net/20.500.11797/TFG5939

Authors:  Murcia Maya, Alicia

Abstract:
Cobalamin, also called vitamin B12, is a water- solu vitamin crucial for protein metabolism. Cobalamin deficiency is one of the most common metabolic disorders in newborns. It can be classified either as a primary deficiency -due to the genetic alteration of transporters or enzymes which catalyze the absorption, transport, or metabolization from vitamins to active cofactors-, or as a secondary deficiency -due to dietary deficiencies. Secondary cobalamin deficiencies in newborns are steadily increasing in Catalonia from 2013 until the present. Despite the fact that 25-35% of mothers have a biochemical alteration related to cobalamin, a 65- 75% of cobalamin deficiencies in newborns cannot be explained.