Effect of curcumin supplementation on the management of insulin resistance in women with polycystic ovary syndrome.

Identifier:  TFM:2240

Handle: https://hdl.handle.net/20.500.11797/TFM2240

Authors:  Guerrero Vivas, Anahí

Abstract:
Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disorder associated with insulin resistance. This systematic review included five randomized clinical trials conducted in Iran between 2015 and 2024, with 12-week interventions. Conventional curcumin favorably reduced glucose, insulin, and HOMA-IR. The nanomicellar formulation showed modest effects when administered alone. However, its combination with metformin showed more consistent and significant reductions in all parameters. Although the results are promising, further evidence from well-designed studies evaluating dosage, formulation, and follow-up is needed to establish robust recommendations.