Novel carbonized mesoporous silicon biosensor for electrochemical pathogen detection

Entity: Universitat Rovira i Virgili (URV)

Confidenciality: No

Education area(s): Nanociència, Materials i Processos - Tecnologia Química de Frontera 

Title in different languages: Biosensor novedoso de silicio mesoporoso carbonizado para la detección electroquímica de patógenos

Abstract: In the present work, we propose a novel PFA (polyfurfuryl alcohol)-modified pSi biosensor for the detection of bacterial 16SrRNA. Electrografting of 4-aminobenzoic hydrazide (4-ABH) provided the most stable sensing platform for the subsequent immobilization of DNA capture probe. The developed DNA sensors measured the blockage as an increase of the charge-transfer resistance, indicating that the hybridization between the capture probe and the target DNA successfully occurred. We have successfully developed a pSi-based electrochemical biosensor able to sensitively and selectively detect a target DNA, which is a first step towards the detection of bacterial pathogens through their specific 16SrRNA growth markers.

Subject: Química

Academic year: 2020-2021

Language: Anglès

Work's public defense date: 2021-09-09

Subject areas: Chemistry

Student: Bujaldón Velasco, Marina

Department: Enginyeria Electrònica, Elèctrica i Automàtica

Creation date in repository: 2021-11-18

Keywords: Porous silicon, polyfurfuryl alcohol, 16rSRNA

Title in original language: Novel carbonized mesoporous silicon biosensor for electrochemical pathogen detection

Access Rights: info:eu-repo/semantics/openAccess

Project director: Prieto Simón, Beatriz