Autor segons l'article: Borrull, F. ; Salas, D. ; Fontanals, N. ; Marcé, R. M.
Departament: Química Analítica i Química Orgànica
Autor/s de la URV: BORRULL BALLARÍN, FRANCESC; Salas, D. ; Fontanals, N. ; MARCÉ RECASENS, ROSA MARIA
Paraules clau: Cationic mixed-mode solid-phase extraction Anionicmixed-mode solid-phase extraction High-resolutionmass spectrometry
Resum: The aim of the present study is to broaden the applications of mixed-mode ion-exchange solid-phase extraction sorbents to extract both basic and acidic compounds simultaneously by combining the sorbents in a single cartridge and developing a simplified extraction procedure. Four different cartridges containing negative and positive charges in the same configuration were evaluated and compared to extract a group of basic, neutral, and acidic pharmaceuticals selected as model compounds. After a thorough optimization of the extraction conditions, the four different cartridges showed to be capable of retaining basic and acidic pharmaceuticals simultaneously through ionic interactions, allowing the introduction of a washing step with 15 mL methanol to eliminate interferences retained by hydrophobic interactions. Using the best combined cartridge, a method was developed, validated, and further applied to environmental waters to demonstrate that the method is promising for the extraction of basic and acidic compounds from very complex samples.
Grup de recerca: Grup de Cromatografia. Aplicacions Mediambientals
Àrees temàtiques: Química Química Chemistry
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 1618-2642
Identificador de l'autor: 0000-0003-2718-9336; ; ; 0000-0002-5667-2899
Data d'alta del registre: 2018-03-01
Pàgina final: 469
Volum de revista: 410
Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
Enllaç font original: https://link.springer.com/article/10.1007/s00216-017-0736-5
Programa de finançament: plan; Excelencia; CTQ2014-52617-P plan; PhD fellowship; BES-2012-057792
DOI de l'article: 10.1007/s00216-017-0736-5
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2018
Pàgina inicial: 459
Tipus de publicació: Article Artículo Article
Repositori URV