Articles producció científica> Química Analítica i Química Orgànica

Recognition and Sensing of Creatinine

  • Dades identificatives

    Identificador: PC:3244
    Autors:
    Guinovart, T.Herández-Alonso, D.Adriaenssens, L.Blondeau, P.Martínez-Belmonte, M.Rius, F.X.Andrade, F.J.Ballester, P.
    Resum:
    Current methods for creatinine quantification present significant drawbacks when aiming to combine accuracy, simplicity and affordability. Here, we report an unprecedented synthetic receptor, a mono-phosphonate aryl-extended calix[4]pyrrole, displaying remarkable affinity for creatinine and the creatininium cation. The receptor works by including the guests in its deep and polar aromatic cavity and establishing directional interactions in three dimensions. When incorporated into a suitable polymeric membrane, this molecule acts as an ionophore, playing the key role in a highly sensitive and selective potentiometric sensor suitable for the determination of creatinine in biological fluids such as urine or plasma in an accurate.
  • Altres:

    Autor segons l'article: Guinovart, T.; Herández-Alonso, D.; Adriaenssens, L.; Blondeau, P.; Martínez-Belmonte, M.; Rius, F.X.; Andrade, F.J.; Ballester, P.
    Departament: Química Analítica i Química Orgànica
    Autor/s de la URV: GUINOVART PAVON, TOMAS DE AQUINO; Herández-Alonso, D.; Adriaenssens, L.; BLONDEAU , PASCAL JEAN CLAUDE LEON; Martínez-Belmonte, M.; RIUS FERRÚS, FRANCISCO JAVIER; ANDRADE , FRANCISCO JAVIER; Ballester, P.
    Resum: Current methods for creatinine quantification present significant drawbacks when aiming to combine accuracy, simplicity and affordability. Here, we report an unprecedented synthetic receptor, a mono-phosphonate aryl-extended calix[4]pyrrole, displaying remarkable affinity for creatinine and the creatininium cation. The receptor works by including the guests in its deep and polar aromatic cavity and establishing directional interactions in three dimensions. When incorporated into a suitable polymeric membrane, this molecule acts as an ionophore, playing the key role in a highly sensitive and selective potentiometric sensor suitable for the determination of creatinine in biological fluids such as urine or plasma in an accurate.
    Grup de recerca: Grup de Quimiometria, Qualimetria i Nanosensors
    Àrees temàtiques: Chemistry Química Química
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 1433-7851
    Identificador de l'autor: 0000-0002-1482-9704; 0000-0001-8673-0247; 0000-0002-8525-0580; 0000-0003-1331-5055; 0000-0003-4592-1252; 0000-0003-4830-1366; 0000-0003-1199-2837; 0000-0001-8377-6610
    Data d'alta del registre: 2018-04-30
    Pàgina final: 2440
    Volum de revista: 55
    Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
    Enllaç font original: https://onlinelibrary.wiley.com/doi/epdf/10.1002/anie.201510136
    Programa de finançament: altres; EU Marie Curie Grant; FlexSens; PCIG09-GA-2011-293538 altres; Gencat Fellowship; FI; BES-2011-048297 plan; CTQ2013-46404-R plan; CTQ2014-52974-REDC plan; CTQ2014-56295- R
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI de l'article: 10.1002/anie.201510136
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2016
    Pàgina inicial: 2435
    Tipus de publicació: Article Artículo Article
  • Paraules clau:

    Creatinina
    Sensors
    Reconeixement molecular
    Chemistry
    Química
    Química
    1433-7851
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