Articles producció científica> Química Analítica i Química Orgànica

Recognition and Sensing of Creatinine

  • Datos identificativos

    Identificador: PC:3244
    Autores:
    Guinovart, T.Herández-Alonso, D.Adriaenssens, L.Blondeau, P.Martínez-Belmonte, M.Rius, F.X.Andrade, F.J.Ballester, P.
    Resumen:
    Current methods for creatinine quantification present significant drawbacks when aiming to combine accuracy, simplicity and affordability. Here, we report an unprecedented synthetic receptor, a mono-phosphonate aryl-extended calix[4]pyrrole, displaying remarkable affinity for creatinine and the creatininium cation. The receptor works by including the guests in its deep and polar aromatic cavity and establishing directional interactions in three dimensions. When incorporated into a suitable polymeric membrane, this molecule acts as an ionophore, playing the key role in a highly sensitive and selective potentiometric sensor suitable for the determination of creatinine in biological fluids such as urine or plasma in an accurate.
  • Otros:

    Autor según el artículo: Guinovart, T.; Herández-Alonso, D.; Adriaenssens, L.; Blondeau, P.; Martínez-Belmonte, M.; Rius, F.X.; Andrade, F.J.; Ballester, P.
    Departamento: Química Analítica i Química Orgànica
    Autor/es de la URV: GUINOVART PAVON, TOMAS DE AQUINO; Herández-Alonso, D.; Adriaenssens, L.; BLONDEAU , PASCAL JEAN CLAUDE LEON; Martínez-Belmonte, M.; RIUS FERRÚS, FRANCISCO JAVIER; ANDRADE , FRANCISCO JAVIER; Ballester, P.
    Resumen: Current methods for creatinine quantification present significant drawbacks when aiming to combine accuracy, simplicity and affordability. Here, we report an unprecedented synthetic receptor, a mono-phosphonate aryl-extended calix[4]pyrrole, displaying remarkable affinity for creatinine and the creatininium cation. The receptor works by including the guests in its deep and polar aromatic cavity and establishing directional interactions in three dimensions. When incorporated into a suitable polymeric membrane, this molecule acts as an ionophore, playing the key role in a highly sensitive and selective potentiometric sensor suitable for the determination of creatinine in biological fluids such as urine or plasma in an accurate.
    Grupo de investigación: Grup de Quimiometria, Qualimetria i Nanosensors
    Áreas temáticas: Chemistry Química Química
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 1433-7851
    Identificador del autor: 0000-0002-1482-9704; 0000-0001-8673-0247; 0000-0002-8525-0580; 0000-0003-1331-5055; 0000-0003-4592-1252; 0000-0003-4830-1366; 0000-0003-1199-2837; 0000-0001-8377-6610
    Fecha de alta del registro: 2018-04-30
    Página final: 2440
    Volumen de revista: 55
    Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
    Enlace a la fuente original: https://onlinelibrary.wiley.com/doi/epdf/10.1002/anie.201510136
    Programa de financiación: altres; EU Marie Curie Grant; FlexSens; PCIG09-GA-2011-293538 altres; Gencat Fellowship; FI; BES-2011-048297 plan; CTQ2013-46404-R plan; CTQ2014-52974-REDC plan; CTQ2014-56295- R
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI del artículo: 10.1002/anie.201510136
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2016
    Página inicial: 2435
    Tipo de publicación: Article Artículo Article
  • Palabras clave:

    Creatinina
    Sensors
    Reconeixement molecular
    Chemistry
    Química
    Química
    1433-7851
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