Articles producció científica> Química Analítica i Química Orgànica

Recognition and Sensing of Creatinine

  • Identification data

    Identifier: PC:3244
    Authors:
    Guinovart, T.Herández-Alonso, D.Adriaenssens, L.Blondeau, P.Martínez-Belmonte, M.Rius, F.X.Andrade, F.J.Ballester, P.
    Abstract:
    Current methods for creatinine quantification present significant drawbacks when aiming to combine accuracy, simplicity and affordability. Here, we report an unprecedented synthetic receptor, a mono-phosphonate aryl-extended calix[4]pyrrole, displaying remarkable affinity for creatinine and the creatininium cation. The receptor works by including the guests in its deep and polar aromatic cavity and establishing directional interactions in three dimensions. When incorporated into a suitable polymeric membrane, this molecule acts as an ionophore, playing the key role in a highly sensitive and selective potentiometric sensor suitable for the determination of creatinine in biological fluids such as urine or plasma in an accurate.
  • Others:

    Author, as appears in the article.: Guinovart, T.; Herández-Alonso, D.; Adriaenssens, L.; Blondeau, P.; Martínez-Belmonte, M.; Rius, F.X.; Andrade, F.J.; Ballester, P.
    Department: Química Analítica i Química Orgànica
    URV's Author/s: GUINOVART PAVON, TOMAS DE AQUINO; Herández-Alonso, D.; Adriaenssens, L.; BLONDEAU , PASCAL JEAN CLAUDE LEON; Martínez-Belmonte, M.; RIUS FERRÚS, FRANCISCO JAVIER; ANDRADE , FRANCISCO JAVIER; Ballester, P.
    Abstract: Current methods for creatinine quantification present significant drawbacks when aiming to combine accuracy, simplicity and affordability. Here, we report an unprecedented synthetic receptor, a mono-phosphonate aryl-extended calix[4]pyrrole, displaying remarkable affinity for creatinine and the creatininium cation. The receptor works by including the guests in its deep and polar aromatic cavity and establishing directional interactions in three dimensions. When incorporated into a suitable polymeric membrane, this molecule acts as an ionophore, playing the key role in a highly sensitive and selective potentiometric sensor suitable for the determination of creatinine in biological fluids such as urine or plasma in an accurate.
    Research group: Grup de Quimiometria, Qualimetria i Nanosensors
    Thematic Areas: Chemistry Química Química
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 1433-7851
    Author identifier: 0000-0002-1482-9704; 0000-0001-8673-0247; 0000-0002-8525-0580; 0000-0003-1331-5055; 0000-0003-4592-1252; 0000-0003-4830-1366; 0000-0003-1199-2837; 0000-0001-8377-6610
    Record's date: 2018-04-30
    Last page: 2440
    Journal volume: 55
    Papper version: info:eu-repo/semantics/acceptedVersion
    Link to the original source: https://onlinelibrary.wiley.com/doi/epdf/10.1002/anie.201510136
    Funding program: altres; EU Marie Curie Grant; FlexSens; PCIG09-GA-2011-293538 altres; Gencat Fellowship; FI; BES-2011-048297 plan; CTQ2013-46404-R plan; CTQ2014-52974-REDC plan; CTQ2014-56295- R
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.1002/anie.201510136
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2016
    First page: 2435
    Publication Type: Article Artículo Article
  • Keywords:

    Creatinina
    Sensors
    Reconeixement molecular
    Chemistry
    Química
    Química
    1433-7851
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