Articles producció científica> Bioquímica i Biotecnologia

Roles of proanthocyanidin rich extracts in obesity

  • Dades identificatives

    Identificador: PC:3389
    Autors:
    Salvadó, MJ
    Resum:
    Obesity is a multifactorial disorder involving an abnormal or excessive amount of body fat. Obese people have a very high probability of developing metabolic syndrome, a condition in which cholesterol, lipid, and glucose levels rise, causing diabetes and heart disease. From the point of view of energy balance, the main contributors to obesity are excessive energy intake, inadequate energy expenditure and metabolic malfunctions. For this reason, health organisations are working to implement policies and plans to promote healthy eating and active living. However, these measures have not yet proven sufficient to combat this worldwide epidemic; therefore, drugs and bioactive compounds are being investigated to complement the existing strategies. In the present review, we discuss the available data regarding the modulation of obesity by proanthocyanidin rich extracts. Because studies with human subjects are very scarce, we focus on studies using laboratory animals. The results of in vitro studies are included because, although they cannot be directly extrapolated to the biological effects of proanthocyanidin, they can reveal some mechanisms of action.
  • Altres:

    Autor segons l'article: Salvadó, MJ
    Departament: Bioquímica i Biotecnologia
    Autor/s de la URV: SALVADÓ ROVIRA, MARIA JOSEPA
    Resum: Obesity is a multifactorial disorder involving an abnormal or excessive amount of body fat. Obese people have a very high probability of developing metabolic syndrome, a condition in which cholesterol, lipid, and glucose levels rise, causing diabetes and heart disease. From the point of view of energy balance, the main contributors to obesity are excessive energy intake, inadequate energy expenditure and metabolic malfunctions. For this reason, health organisations are working to implement policies and plans to promote healthy eating and active living. However, these measures have not yet proven sufficient to combat this worldwide epidemic; therefore, drugs and bioactive compounds are being investigated to complement the existing strategies. In the present review, we discuss the available data regarding the modulation of obesity by proanthocyanidin rich extracts. Because studies with human subjects are very scarce, we focus on studies using laboratory animals. The results of in vitro studies are included because, although they cannot be directly extrapolated to the biological effects of proanthocyanidin, they can reveal some mechanisms of action.
    Grup de recerca: Grup de Recerca en Nutrigenòmica
    Àrees temàtiques: Bioquímica i biotecnologia Bioquímica y tecnología Biochemistry and technology
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 2042-6496
    Identificador de l'autor: 0000-0003-3883-3326
    Data d'alta del registre: 2019-01-17
    Pàgina final: 1071
    Volum de revista: 2015
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://pubs.rsc.org/en/content/articlelanding/2015/FO/C4FO01035C#!divAbstract
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI de l'article: 10.1039/c4fo01035c
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2015
    Pàgina inicial: 1053
    Tipus de publicació: Article Artículo Article
  • Paraules clau:

    Raïms--Ús terapèutic
    Proantocianidines
    Bioquímica i biotecnologia
    Bioquímica y tecnología
    Biochemistry and technology
    2042-6496
  • Documents:

  • Cerca a google

    Search to google scholar