Autor segons l'article: Aparicio, J.; Terrasa, J.; Duran, I.; Germa-Lluch, J. R.; Girones, R.; Gonzalez-Billalabeitia, E.; Guma, J.; Maroto, P.; Pinto, A.; Garcia-del-Muro, X.;
Departament: Medicina i Cirurgia
Autor/s de la URV: Gumà Padró, José
Paraules clau: Tumors Testicular cancer Term-follow-up Surgery Stage-i seminoma Risk Randomized-trial Prognostic-factors Phase-iii Lymph-node dissection Germ-cell tumor Chemotherapy Adjuvant treatment
Resum: Testicular cancer represents the most common malignancy in males aged 15-34 years and is considered a model of curable neoplasm. Maintaining success, reducing treatment burden, and focusing on survivorship are then key objectives. Inguinal orchiectomy is the first recommended maneuver that has both diagnostic and therapeutic aims. Most patients are diagnosed with stage I disease (confined to the testicle). Close surveillance and selective, short-course adjuvant chemotherapy are accepted alternatives for these cases. In patients with more advanced disease (stages II and III), 3-4 courses of cisplatin-based chemotherapy (according to IGCCCG risk classification) followed by the judicious surgical removal of residual masses represent the cornerstone of therapy. Poor-risk patients and those failing a first-line therapy should be referred to specialized tertiary centers. Paclitaxel-based conventional chemotherapy and high-dose chemotherapy plus autologous hematopoietic support can cure a proportion of patients with relapsing or refractory disease.
Àrees temàtiques: Saúde coletiva Oncology Odontología Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Farmacia Engenharias ii Ciências biológicas ii Ciências biológicas i Cancer research Biotecnología
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 1699048X
Adreça de correu electrònic de l'autor: jose.guma@urv.cat
Identificador de l'autor: 0000-0001-7541-9832
Data d'alta del registre: 2024-09-07
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://link.springer.com/article/10.1007/s12094-016-1566-1
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Clinical & Translational Oncology. 18 (12): 1187-1196
Referència de l'ítem segons les normes APA: Aparicio, J.; Terrasa, J.; Duran, I.; Germa-Lluch, J. R.; Girones, R.; Gonzalez-Billalabeitia, E.; Guma, J.; Maroto, P.; Pinto, A.; Garcia-del-Muro, X (2016). SEOM clinical guidelines for the management of germ cell testicular cancer (2016). Clinical & Translational Oncology, 18(12), 1187-1196. DOI: 10.1007/s12094-016-1566-1
DOI de l'article: 10.1007/s12094-016-1566-1
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2016
Tipus de publicació: Journal Publications
Repositori URV