Autor según el artículo: Aparicio, J.; Terrasa, J.; Duran, I.; Germa-Lluch, J. R.; Girones, R.; Gonzalez-Billalabeitia, E.; Guma, J.; Maroto, P.; Pinto, A.; Garcia-del-Muro, X.;
Departamento: Medicina i Cirurgia
Autor/es de la URV: Gumà Padró, José
Palabras clave: Tumors Testicular cancer Term-follow-up Surgery Stage-i seminoma Risk Randomized-trial Prognostic-factors Phase-iii Lymph-node dissection Germ-cell tumor Chemotherapy Adjuvant treatment
Resumen: Testicular cancer represents the most common malignancy in males aged 15-34 years and is considered a model of curable neoplasm. Maintaining success, reducing treatment burden, and focusing on survivorship are then key objectives. Inguinal orchiectomy is the first recommended maneuver that has both diagnostic and therapeutic aims. Most patients are diagnosed with stage I disease (confined to the testicle). Close surveillance and selective, short-course adjuvant chemotherapy are accepted alternatives for these cases. In patients with more advanced disease (stages II and III), 3-4 courses of cisplatin-based chemotherapy (according to IGCCCG risk classification) followed by the judicious surgical removal of residual masses represent the cornerstone of therapy. Poor-risk patients and those failing a first-line therapy should be referred to specialized tertiary centers. Paclitaxel-based conventional chemotherapy and high-dose chemotherapy plus autologous hematopoietic support can cure a proportion of patients with relapsing or refractory disease.
Áreas temáticas: Saúde coletiva Oncology Odontología Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Farmacia Engenharias ii Ciências biológicas ii Ciências biológicas i Cancer research Biotecnología
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 1699048X
Direcció de correo del autor: jose.guma@urv.cat
Identificador del autor: 0000-0001-7541-9832
Fecha de alta del registro: 2024-09-07
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://link.springer.com/article/10.1007/s12094-016-1566-1
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Clinical & Translational Oncology. 18 (12): 1187-1196
Referencia de l'ítem segons les normes APA: Aparicio, J.; Terrasa, J.; Duran, I.; Germa-Lluch, J. R.; Girones, R.; Gonzalez-Billalabeitia, E.; Guma, J.; Maroto, P.; Pinto, A.; Garcia-del-Muro, X (2016). SEOM clinical guidelines for the management of germ cell testicular cancer (2016). Clinical & Translational Oncology, 18(12), 1187-1196. DOI: 10.1007/s12094-016-1566-1
DOI del artículo: 10.1007/s12094-016-1566-1
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2016
Tipo de publicación: Journal Publications