Articles producció científica> Medicina i Cirurgia

SEOM clinical guidelines for the management of germ cell testicular cancer (2016)

  • Identification data

    Identifier: imarina:2621837
    Authors:
    Aparicio, J.Terrasa, J.Duran, I.Germa-Lluch, J. R.Girones, R.Gonzalez-Billalabeitia, E.Guma, J.Maroto, P.Pinto, A.Garcia-del-Muro, X.
    Abstract:
    Testicular cancer represents the most common malignancy in males aged 15-34 years and is considered a model of curable neoplasm. Maintaining success, reducing treatment burden, and focusing on survivorship are then key objectives. Inguinal orchiectomy is the first recommended maneuver that has both diagnostic and therapeutic aims. Most patients are diagnosed with stage I disease (confined to the testicle). Close surveillance and selective, short-course adjuvant chemotherapy are accepted alternatives for these cases. In patients with more advanced disease (stages II and III), 3-4 courses of cisplatin-based chemotherapy (according to IGCCCG risk classification) followed by the judicious surgical removal of residual masses represent the cornerstone of therapy. Poor-risk patients and those failing a first-line therapy should be referred to specialized tertiary centers. Paclitaxel-based conventional chemotherapy and high-dose chemotherapy plus autologous hematopoietic support can cure a proportion of patients with relapsing or refractory disease.
  • Others:

    Author, as appears in the article.: Aparicio, J.; Terrasa, J.; Duran, I.; Germa-Lluch, J. R.; Girones, R.; Gonzalez-Billalabeitia, E.; Guma, J.; Maroto, P.; Pinto, A.; Garcia-del-Muro, X.;
    Department: Medicina i Cirurgia
    URV's Author/s: Gumà Padró, José
    Keywords: Tumors Testicular cancer Term-follow-up Surgery Stage-i seminoma Risk Randomized-trial Prognostic-factors Phase-iii Lymph-node dissection Germ-cell tumor Chemotherapy Adjuvant treatment
    Abstract: Testicular cancer represents the most common malignancy in males aged 15-34 years and is considered a model of curable neoplasm. Maintaining success, reducing treatment burden, and focusing on survivorship are then key objectives. Inguinal orchiectomy is the first recommended maneuver that has both diagnostic and therapeutic aims. Most patients are diagnosed with stage I disease (confined to the testicle). Close surveillance and selective, short-course adjuvant chemotherapy are accepted alternatives for these cases. In patients with more advanced disease (stages II and III), 3-4 courses of cisplatin-based chemotherapy (according to IGCCCG risk classification) followed by the judicious surgical removal of residual masses represent the cornerstone of therapy. Poor-risk patients and those failing a first-line therapy should be referred to specialized tertiary centers. Paclitaxel-based conventional chemotherapy and high-dose chemotherapy plus autologous hematopoietic support can cure a proportion of patients with relapsing or refractory disease.
    Thematic Areas: Saúde coletiva Oncology Odontología Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Farmacia Engenharias ii Ciências biológicas ii Ciências biológicas i Cancer research Biotecnología
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 1699048X
    Author's mail: jose.guma@urv.cat
    Author identifier: 0000-0001-7541-9832
    Record's date: 2024-09-07
    Papper version: info:eu-repo/semantics/publishedVersion
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Clinical & Translational Oncology. 18 (12): 1187-1196
    APA: Aparicio, J.; Terrasa, J.; Duran, I.; Germa-Lluch, J. R.; Girones, R.; Gonzalez-Billalabeitia, E.; Guma, J.; Maroto, P.; Pinto, A.; Garcia-del-Muro, X (2016). SEOM clinical guidelines for the management of germ cell testicular cancer (2016). Clinical & Translational Oncology, 18(12), 1187-1196. DOI: 10.1007/s12094-016-1566-1
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2016
    Publication Type: Journal Publications
  • Keywords:

    Cancer Research,Medicine (Miscellaneous),Oncology
    Tumors
    Testicular cancer
    Term-follow-up
    Surgery
    Stage-i seminoma
    Risk
    Randomized-trial
    Prognostic-factors
    Phase-iii
    Lymph-node dissection
    Germ-cell tumor
    Chemotherapy
    Adjuvant treatment
    Saúde coletiva
    Oncology
    Odontología
    Medicine (miscellaneous)
    Medicina veterinaria
    Medicina ii
    Medicina i
    Farmacia
    Engenharias ii
    Ciências biológicas ii
    Ciências biológicas i
    Cancer research
    Biotecnología
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