Autor segons l'article: Heredia, Luis; Belles, Montserrat; LLovet, Maria Isabel; Domingo, Jose L; Linares, Victoria
Departament: Ciències Mèdiques Bàsiques
Autor/s de la URV: Bellés Mateu, Montserrat / Domingo Roig, José Luis / Heredia Santaella, Luis / Linares Vidal, M. Victoria
Paraules clau: Time factors Spatial memory Postnatal Plasticizers Phenols Motor activity Mice, inbred c57bl Mice Memory disorders Maze learning Ionizing radiation Ionising radiation Estudios de toxicidad perinatal y postnatal. Dose-response relationship, radiation Dose-response relationship, drug Cesium-137 Cesium radioisotopes Brain Bisphenol a Benzhydryl compounds Behavior, animal Behavior Anxiety Animals, newborn Animals Animal behavior Age factors 137-cesium mice ionizing radiation bisphenol a behavior 137-cesium
Resum: Bisphenol A (BPA) is the most important plasticizer used in many household products such as polycarbonate plastics or epoxy resins. Public and scientific concerns exist regarding the possibility that the neonatal exposure to BPA may contribute to neurobehavioral disorders. On the other hand, there is little information on the effects of low doses of ionizing radiation during critical phases of postnatal brain development, as well as the combination of radiation and environmental chemicals. In this study, C57BL/6J mice were exposed to low doses of internal radiation ((137)Cs), and/or BPA on postnatal day 10 (PND10). At the age of two months, animals were submitted to several tests to assess anxiety, activity, learning, and memory. Results showed that exposure to (137)Cs, alone or in combination with BPA, increased the anxiety-like of the animals without changing the activity levels. Animals exposed to (137)Cs showed impaired learning, and spatial memory, an impairment that was not observed in the groups co-exposed to BPA.
Àrees temàtiques: Toxicology Saúde coletiva Química Psicología Pharmacology & pharmacy Odontología Medicina veterinaria Medicina ii Medicina i Materiais Interdisciplinar General medicine Farmacia Ensino Engenharias iii Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciência da computação Biotecnología Biodiversidade
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 0300483X
Adreça de correu electrònic de l'autor: luis.heredia@urv.cat luis.heredia@urv.cat joseluis.domingo@urv.cat mvictoria.linares@urv.cat montserrat.belles@urv.cat
Identificador de l'autor: 0000-0001-9330-9418 0000-0001-9330-9418 0000-0001-6647-9470 0000-0003-4170-4197 0000-0002-9282-2989
Data d'alta del registre: 2024-10-12
Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
Enllaç font original: https://www.sciencedirect.com/science/article/abs/pii/S0300483X15300597
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Toxicology. 340 10-16
Referència de l'ítem segons les normes APA: Heredia, Luis; Belles, Montserrat; LLovet, Maria Isabel; Domingo, Jose L; Linares, Victoria (2016). Behavioral effects in mice of postnatal exposure to low-doses of 137-cesium and bisphenol A. Toxicology, 340(), 10-16. DOI: 10.1016/j.tox.2015.12.002
DOI de l'article: 10.1016/j.tox.2015.12.002
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2016
Tipus de publicació: Journal Publications
Repositori URV