Autor según el artículo: Heredia L; Bellés M; LLovet MI; Domingo JL; Linares V

Departamento: Ciències Mèdiques Bàsiques

Autor/es de la URV: Bellés Mateu, Montserrat / Domingo Roig, José Luis / Heredia Santaella, Luis / Linares Vidal, M. Victoria

Palabras clave: Postnatal Mice Ionizing radiation Ionising radiation Estudios de toxicidad perinatal y postnatal. Cesium-137 Bisphenol a Behavior Animal behavior 137-cesium mice ionizing radiation bisphenol a behavior 137-cesium

Resumen: Bisphenol A (BPA) is the most important plasticizer used in many household products such as polycarbonate plastics or epoxy resins. Public and scientific concerns exist regarding the possibility that the neonatal exposure to BPA may contribute to neurobehavioral disorders. On the other hand, there is little information on the effects of low doses of ionizing radiation during critical phases of postnatal brain development, as well as the combination of radiation and environmental chemicals. In this study, C57BL/6J mice were exposed to low doses of internal radiation ((137)Cs), and/or BPA on postnatal day 10 (PND10). At the age of two months, animals were submitted to several tests to assess anxiety, activity, learning, and memory. Results showed that exposure to (137)Cs, alone or in combination with BPA, increased the anxiety-like of the animals without changing the activity levels. Animals exposed to (137)Cs showed impaired learning, and spatial memory, an impairment that was not observed in the groups co-exposed to BPA.

Áreas temáticas: Toxicology Saúde coletiva Química Psicología Pharmacology & pharmacy Odontología Medicina veterinaria Medicina ii Medicina i Materiais Interdisciplinar General medicine Farmacia Ensino Engenharias iii Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciência da computação Biotecnología Biodiversidade

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 0300483X

Direcció de correo del autor: luis.heredia@urv.cat montserrat.belles@urv.cat mvictoria.linares@urv.cat joseluis.domingo@urv.cat

Identificador del autor: 0000-0001-9330-9418 0000-0002-9282-2989 0000-0003-4170-4197 0000-0001-6647-9470

Fecha de alta del registro: 2023-02-22

Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion

Enlace a la fuente original: https://www.sciencedirect.com/science/article/abs/pii/S0300483X15300597

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Toxicology. 340 10-16

Referencia de l'ítem segons les normes APA: Heredia L; Bellés M; LLovet MI; Domingo JL; Linares V (2016). Behavioral effects in mice of postnatal exposure to low-doses of 137-cesium and bisphenol A. Toxicology, 340(), 10-16. DOI: 10.1016/j.tox.2015.12.002

DOI del artículo: 10.1016/j.tox.2015.12.002

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2016

Tipo de publicación: Journal Publications