Opportune gem-silylborylation of carbonyl compounds: a modular and stereocontrolled entry to tetrasubstituted olefins

Identificador:  imarina:3658141

Handle: https://hdl.handle.net/20.500.11797/imarina3658141

Autors:  La Cascia, E; Cuenca, AB; Fernández, E

Resum:
An easy access to highly versatile gem-silylboro-nate synthons is achieved by means of an new olefination reagent, HC(B pin)2(SiMe3). Subsequent silicon or boron-based selective functionalization allows for the modular and stereocontrolled synthesis of all-carbon tetrasubstitut-ed alkenes.Aparticular attraction of this approach is the iodode silylation reaction, whichbecomes apivotaltool for C-Si functionalization.