Autor segons l'article: Méndez L., Ciordia S., Fernández M., Juárez S., Ramos A., Pazos M., Gallardo J., Torres J., Nogués M., Medina I.
Departament: Ciències Mèdiques Bàsiques
Autor/s de la URV: Nogués Llort, Maria Rosa
Paraules clau: Wistar kyoto rat Liver protein regulation High-fat, high-sucrose diet Grape polyphenols Fish oils Bioactive compounds liver protein regulation high-fat, high-sucrose diet grape polyphenols fish oils bioactive compounds
Resum: This study considered the physiological modulation of liver proteins due to the supplementation with fish oils under two dietary backgrounds: standard or high in fat and sucrose (HFHS), and their combination with grape polyphenols. By using a quantitative proteomics approach, we showed that the capacity of the supplements for regulating proteins depended on the diet; namely, 10 different proteins changed into standard diets, while 45 changed into the HFHS diets and only scarcely proteins were found altered in common. However, in both contexts, fish oils were the main regulatory force, although the addition of polyphenols was able to modulate some fish oils' effects. Moreover, we demonstrated the ability of fish oils and their combination with grape polyphenols in improving biochemical parameters and reducing lipogenesis and glycolysis enzymes, enhancing fatty acid beta-oxidation and insulin signaling and ameliorating endoplasmic reticulum stress and protein oxidation when they are included in an unhealthy diet.
Àrees temàtiques: Saúde coletiva Química Odontología Nutrition and dietetics Nutrition & dietetics Nutrição Molecular biology Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Farmacia Enfermagem Endocrinology, diabetes and metabolism Educação física Clinical biochemistry Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología Biochemistry & molecular biology Biochemistry
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 09552863
Adreça de correu electrònic de l'autor: mariarosa.nogues@urv.cat
Identificador de l'autor: 0000-0003-4626-5672
Pàgina final: 97
Data d'alta del registre: 2023-02-18
Volum de revista: 41
Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
Enllaç font original: https://www.sciencedirect.com/science/article/abs/pii/S0955286316302674?via%3Dihub
Referència a l'article segons font original: Journal Of Nutritional Biochemistry. 41 84-97
Referència de l'ítem segons les normes APA: Méndez L., Ciordia S., Fernández M., Juárez S., Ramos A., Pazos M., Gallardo J., Torres J., Nogués M., Medina I. (2017). Changes in liver proteins of rats fed standard and high-fat and sucrose diets induced by fish omega-3 PUFAs and their combination with grape polyphenols according to quantitative proteomics. Journal Of Nutritional Biochemistry, 41(), 84-97. DOI: 10.1016/j.jnutbio.2016.12.005
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI de l'article: 10.1016/j.jnutbio.2016.12.005
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2017
Pàgina inicial: 84
Tipus de publicació: Journal Publications
Repositori URV