Codi de projecte: CTQ2013-46404-R
Data d'alta del registre: 2023-02-18
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
URL Document de llicència: http://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Lab On A Chip. 17 (14): 2500-2507
Referència de l'ítem segons les normes APA: Cánovas R; Parrilla M.; Blondeau P.; Andrade F.J. (2017). A novel wireless paper-based potentiometric platform for monitoring glucose in blood. Lab On A Chip, 17(14), 2500-2507. DOI: 10.1039/c7lc00339k
Acrònim: 'Plataformas electroquímicas descentralizadas'
Tipus de publicació: Journal Publications
Autor segons l'article: Cánovas R; Parrilla M.; Blondeau P.; Andrade F.J.
Departament: Química Analítica i Química Orgànica
Acrònim 2: HOMESENS
Autor/s de la URV: Andrade, Francisco Javier / Blondeau, Pascal Jean Claude Leon
Resum: A novel low-cost, compact and sensitive paper-based platform for the accurate monitoring of glucose in biological fluids is presented. Paper-based working and reference electrodes are combined to build a whole potentiometric cell, which also fits a sampling module for simple and fast determination of glucose in a single drop of blood. The working electrode is built using a platinized filter paper coated with a Nafion membrane that entraps the enzyme glucose oxidase; the reference electrode is made by casting a polyvinylbutyral-based membrane onto a conductive paper. The system works by detecting the hydrogen peroxide generated as a result of the enzymatic reaction. Selectivity is achieved due to the permselective behaviour of Nafion, while a significant enhancement of the sensitivity is reached by exploiting the Donnan-coupled formal potential. Under optimum conditions, a sensitivity of −95.9 ± 4.8 mV per decade in the 0.3-3 mM range is obtained. Validation of the measurements has been performed against standard methods in human serum and blood. Final integration with a wireless reader allows for truly in situ measurements with a less than 2 minute procedure including a two-point calibration, washing and measurement. This low-cost analytical device opens up new prospects for rapid diagnostic results in nonlaboratory settings.
Acció del programa de finançament 2: Proyecto de I+D
Àrees temàtiques: Química Nanoscience and nanotechnology Nanoscience & nanotechnology Materiais Interdisciplinar Instruments & instrumentation General medicine General chemistry Farmacia Engenharias iv Engenharias ii Chemistry, multidisciplinary Chemistry, analytical Chemistry (miscellaneous) Chemistry (all) Biotecnología Biomedical engineering Bioengineering Biochemistry Biochemical research methods Astronomia / física
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 14730189
Adreça de correu electrònic de l'autor: pascal.blondeau@urv.cat franciscojavier.andrade@urv.cat
Identificador de l'autor: 0000-0003-1331-5055 0000-0003-1199-2837
Codi del projecte 2: CTQ2016-77128-R
Programa de finançament 2: Programa Estatal de Investigación, Desarrollo e Innovación Orientada a los Retos de la Sociedad (Agencia Estatal de Investigación - Ministerio de Economía, Industria y Competitividad)
Enllaç font original: https://pubs.rsc.org/en/content/articlelanding/2017/lc/c7lc00339k#!divAbstract
Programa de finançament: Programa Estatal de Investigación, Desarrollo e Innovación Orientada a los Retos de la Sociedad (Agencia Estatal de Investigación - Ministerio de Economía, Industria y Competitividad)
DOI de l'article: 10.1039/c7lc00339k
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2017
Acció del programa de finançament: Proyecto de investigación
Repositori URV