Autor segons l'article: Lligadas G, Enayati M, Grama S, Smail R, Sherman SE, Percec V
Departament: Química Analítica i Química Orgànica
e-ISSN: 1526-4602
Autor/s de la URV: Lligadas Puig, Gerard
Paraules clau: Vinyl-chloride Single-electron-transfer Methyl acrylate Living radical polymerization Free radical reactions Dramatic acceleration Divergent synthesis Dendritic macromolecules Cu(0) wire Conventional monomers Biology Amide functional initiators
Resum: To continue expanding the use of Single Electron Transfer-Living Radical Polymerization (SET-LRP) in applications at the interface between macromolecular science, biomacromolecules, biology and medicine, it is essential to develop novel initiators that do not compromise the structural stability of synthesized polymers in biological environments. Here, we report that stable 2-bromopropionyl peptoid-type initiators such as 1,4-bis(2-bromopropionyl)piperazine and 4-(2-bromopropionyl)morpholine are an alternative that meets the standards reached by the well-known secondary and tertiary ¿-haloester-type initiators in terms of excellent control over molecular weight evolution and distribution as well as polymer chain ends. SET-LRP methodologies in organic, aqueous, and biphasic organic-aqueous media were evaluated for this purpose.
Àrees temàtiques: Química Polymers and plastics Polymer science Medicina ii Materials chemistry Materiais Interdisciplinar Farmacia Engenharias iv Engenharias ii Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, organic Biotecnología Biomaterials Bioengineering Biochemistry & molecular biology Astronomia / física
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 1525-7797
Adreça de correu electrònic de l'autor: gerard.lligadas@urv.cat
Identificador de l'autor: 0000-0002-8519-1840
Data d'alta del registre: 2024-09-07
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://pubs.acs.org/doi/10.1021/acs.biomac.7b00722
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Biomacromolecules. 18 (8): 2610-2622
Referència de l'ítem segons les normes APA: Lligadas G, Enayati M, Grama S, Smail R, Sherman SE, Percec V (2017). Ultrafast SET-LRP with Peptoid Cytostatic Drugs as Monofunctional and Bifunctional Initiators. Biomacromolecules, 18(8), 2610-2622. DOI: 10.1021/acs.biomac.7b00722
DOI de l'article: 10.1021/acs.biomac.7b00722
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2017
Tipus de publicació: Journal Publications
Repositori URV