Autor según el artículo: Lligadas G, Enayati M, Grama S, Smail R, Sherman SE, Percec V

Departamento: Química Analítica i Química Orgànica

e-ISSN: 1526-4602

Autor/es de la URV: Lligadas Puig, Gerard

Palabras clave: Vinyl-chloride Single-electron-transfer Methyl acrylate Living radical polymerization Free radical reactions Dramatic acceleration Divergent synthesis Dendritic macromolecules Cu(0) wire Conventional monomers Biology Amide functional initiators

Resumen: To continue expanding the use of Single Electron Transfer-Living Radical Polymerization (SET-LRP) in applications at the interface between macromolecular science, biomacromolecules, biology and medicine, it is essential to develop novel initiators that do not compromise the structural stability of synthesized polymers in biological environments. Here, we report that stable 2-bromopropionyl peptoid-type initiators such as 1,4-bis(2-bromopropionyl)piperazine and 4-(2-bromopropionyl)morpholine are an alternative that meets the standards reached by the well-known secondary and tertiary ¿-haloester-type initiators in terms of excellent control over molecular weight evolution and distribution as well as polymer chain ends. SET-LRP methodologies in organic, aqueous, and biphasic organic-aqueous media were evaluated for this purpose.

Áreas temáticas: Química Polymers and plastics Polymer science Medicina ii Materials chemistry Materiais Interdisciplinar Farmacia Engenharias iv Engenharias ii Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, organic Biotecnología Biomaterials Bioengineering Biochemistry & molecular biology Astronomia / física

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 1525-7797

Direcció de correo del autor: gerard.lligadas@urv.cat

Identificador del autor: 0000-0002-8519-1840

Fecha de alta del registro: 2023-02-22

Versión del articulo depositado: info:eu-repo/semantics/publishedVersion

Enlace a la fuente original: https://pubs.acs.org/doi/10.1021/acs.biomac.7b00722

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Biomacromolecules. 18 (8): 2610-2622

Referencia de l'ítem segons les normes APA: Lligadas G, Enayati M, Grama S, Smail R, Sherman SE, Percec V (2017). Ultrafast SET-LRP with Peptoid Cytostatic Drugs as Monofunctional and Bifunctional Initiators. Biomacromolecules, 18(8), 2610-2622. DOI: 10.1021/acs.biomac.7b00722

DOI del artículo: 10.1021/acs.biomac.7b00722

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2017

Tipo de publicación: Journal Publications