Autor segons l'article: Candido Fernandez-Cao, Jose; Arija, Victoria; Aranda, Nuria; Bullo, Monica; Basora, Josep; Angel Martinez-Gonzalez, Miguel; Diez-Espino, Javier; Salas-Salvado, Jordi
Departament: Bioquímica i Biotecnologia Ciències Mèdiques Bàsiques Medicina i Cirurgia
Autor/s de la URV: Aranda Pons, Núria / Arija Val, Maria Victoria / Basora Gallisa, Josep / Bulló Bonet, Mònica / Salas Salvadó, Jorge
Resum: Background: Several epidemiological studies have observed an increased risk of type 2 diabetes mellitus (T2DM) among subjects with a higher consumption of red and processed meat. Heme iron intake has been directly associated with a higher risk of T2DM in healthy adult Chinese and U.S populations. The objective of the present study was to evaluate the association between heme iron intake and the incidence of T2DM in a Mediterranean population at high cardiovascular risk. Methods. We assessed a subset of participants in the PREDIMED trial as an observational cohort, followed up for a maximum of eight years. We initially included 1073 non-diabetic subjects (57.1% women) aged 67.3 ± 6.0 years, at high cardiovascular risk. Diet was assessed at the study baseline using a validated, semi-quantitative food frequency questionnaire. Results: During the follow-up period 131 diabetics were newly diagnosed. The risk of developing T2DM was assessed using baseline heme iron intake and proportional hazard models, first unadjusted, then adjusted for energy, and finally adjusted for dietary, anthropometric, socio-demographic and lifestyle variables. Significant direct associations with the incidence of T2DM were found for heme iron (Hazard Ratio [HR] 1.30, 95% confidence interval [CI], 1.02 to 1.66). Secondarily, we have also observed that coffee (HR:0.93, 95% CI, 0.89 to 0.98) and alcoholic beverages (HR: 1.02, 95% CI, 1.01 to 1.04) were also found to reduce and increase the risk of T2DM, respectively. Conclusion: High dietary intake of heme iron was associated with an increased risk of developing T2DM in a Mediterranean population at high cardiovascular risk. Trial registration. Identifier: ISRCTN35739639. © 2013 Fernandez-Cao et al.; licensee BioMed Central Ltd.
Àrees temàtiques: Zootecnia / recursos pesqueiros Sociología Serviço social Saúde coletiva Química Public, environmental & occupational health Public health, environmental and occupational health Psicología Planejamento urbano e regional / demografia Odontología Nutrição Medicina iii Medicina ii Medicina i Interdisciplinar Geociências Farmacia Ensino Enfermagem Educação física Educação Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciência de alimentos Biotecnología Astronomia / física Antropologia / arqueologia Administração, ciências contábeis e turismo Administração pública e de empresas, ciências contábeis e turismo
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 14712458
Adreça de correu electrònic de l'autor: josep.basora@urv.cat nuria.aranda@urv.cat monica.bullo@urv.cat josep.basora@urv.cat jordi.salas@urv.cat victoria.arija@urv.cat
Identificador de l'autor: 0000-0001-9708-747X 0000-0002-0218-7046 0000-0003-2700-7459 0000-0002-1758-0975
Data d'alta del registre: 2024-10-12
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://bmcpublichealth.biomedcentral.com/articles/10.1186/1471-2458-13-1042
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Bmc Public Health. 13 (1): 1042-
Referència de l'ítem segons les normes APA: Candido Fernandez-Cao, Jose; Arija, Victoria; Aranda, Nuria; Bullo, Monica; Basora, Josep; Angel Martinez-Gonzalez, Miguel; Diez-Espino, Javier; Salas (2013). Heme iron intake and risk of new-onset diabetes in a Mediterranean population at high risk of cardiovascular disease: An observational cohort analysis. Bmc Public Health, 13(1), 1042-. DOI: 10.1186/1471-2458-13-1042
DOI de l'article: 10.1186/1471-2458-13-1042
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2013
Tipus de publicació: Journal Publications
Repositori URV