Articles producció científica> Química Analítica i Química Orgànica

Ni-Catalyzed Carboxylation of Aziridines en Route to beta-Amino Acids

  • Dades identificatives

    Identificador: imarina:9189730
    Autors:
    Davies, JacobJanssen-Mueller, DanielZimin, Dmitry P.Day, Craig S.Yanagi, TomoyukiElfert, JonasMartin, Ruben
    Resum:
    A Ni-catalyzed reductive carboxylation of N-substituted aziridines with CO2 at atmospheric pressure is disclosed. The protocol is characterized by its mild conditions, experimental ease, and exquisite chemo- and regioselectivity pattern, thus unlocking a new catalytic blueprint to access beta-amino acids, important building blocks with considerable potential as peptidomimetics.
  • Altres:

    Autor segons l'article: Davies, Jacob; Janssen-Mueller, Daniel; Zimin, Dmitry P.; Day, Craig S.; Yanagi, Tomoyuki; Elfert, Jonas; Martin, Ruben;
    Departament: Química Analítica i Química Orgànica
    Autor/s de la URV: Day, Craig
    Paraules clau: Unclassified drug Regioselectivity Reaction time Peptidomimetics Organic compounds Nickel compounds Nickel Limit of detection En-route Deprotection reaction Cyclization Controlled study Chemoselectivity Chemo-and regioselectivities Chemical phenomena Catalysis Carboxylation Carbon dioxide Building blockes Beta leucine Beta homotyrosine Beta homotryptophan Beta homophenylalanine Beta homoleucine Beta homoglutamate methyl ester Beta homoalanine Beta amino acids Beta amino acid Aziridines Aziridine derivative Atmospheric pressure Article Amino acids
    Resum: A Ni-catalyzed reductive carboxylation of N-substituted aziridines with CO2 at atmospheric pressure is disclosed. The protocol is characterized by its mild conditions, experimental ease, and exquisite chemo- and regioselectivity pattern, thus unlocking a new catalytic blueprint to access beta-amino acids, important building blocks with considerable potential as peptidomimetics.
    Àrees temàtiques: Química Materiais Interdisciplinar General chemistry Farmacia Engenharias iv Engenharias iii Engenharias ii Colloid and surface chemistry Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, multidisciplinary Chemistry (miscellaneous) Chemistry (all) Chemistry Catalysis Biochemistry Astronomia / física
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    Adreça de correu electrònic de l'autor: craig.day@estudiants.urv.cat
    Identificador de l'autor: 0000-0002-6931-0280
    Pàgina final: 4954
    Data d'alta del registre: 2024-07-27
    Volum de revista: 143
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://pubs.acs.org/doi/10.1021/jacs.1c01916
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Journal Of The American Chemical Society. 143 (13): 4949-4954
    Referència de l'ítem segons les normes APA: Davies, Jacob; Janssen-Mueller, Daniel; Zimin, Dmitry P.; Day, Craig S.; Yanagi, Tomoyuki; Elfert, Jonas; Martin, Ruben; (2021). Ni-Catalyzed Carboxylation of Aziridines en Route to beta-Amino Acids. Journal Of The American Chemical Society, 143(13), 4949-4954. DOI: 10.1021/jacs.1c01916
    DOI de l'article: 10.1021/jacs.1c01916
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2021
    Pàgina inicial: 4949
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Biochemistry,Catalysis,Chemistry,Chemistry (Miscellaneous),Chemistry, Multidisciplinary,Colloid and Surface Chemistry
    Unclassified drug
    Regioselectivity
    Reaction time
    Peptidomimetics
    Organic compounds
    Nickel compounds
    Nickel
    Limit of detection
    En-route
    Deprotection reaction
    Cyclization
    Controlled study
    Chemoselectivity
    Chemo-and regioselectivities
    Chemical phenomena
    Catalysis
    Carboxylation
    Carbon dioxide
    Building blockes
    Beta leucine
    Beta homotyrosine
    Beta homotryptophan
    Beta homophenylalanine
    Beta homoleucine
    Beta homoglutamate methyl ester
    Beta homoalanine
    Beta amino acids
    Beta amino acid
    Aziridines
    Aziridine derivative
    Atmospheric pressure
    Article
    Amino acids
    Química
    Materiais
    Interdisciplinar
    General chemistry
    Farmacia
    Engenharias iv
    Engenharias iii
    Engenharias ii
    Colloid and surface chemistry
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Ciência de alimentos
    Chemistry, multidisciplinary
    Chemistry (miscellaneous)
    Chemistry (all)
    Chemistry
    Catalysis
    Biochemistry
    Astronomia / física
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