Autor según el artículo: Davies, Jacob; Janssen-Mueller, Daniel; Zimin, Dmitry P.; Day, Craig S.; Yanagi, Tomoyuki; Elfert, Jonas; Martin, Ruben;
Departamento: Química Analítica i Química Orgànica
Autor/es de la URV: Day, Craig
Palabras clave: Unclassified drug Regioselectivity Reaction time Peptidomimetics Organic compounds Nickel compounds Nickel Limit of detection En-route Deprotection reaction Cyclization Controlled study Chemoselectivity Chemo-and regioselectivities Chemical phenomena Catalysis Carboxylation Carbon dioxide Building blockes Beta leucine Beta homotyrosine Beta homotryptophan Beta homophenylalanine Beta homoleucine Beta homoglutamate methyl ester Beta homoalanine Beta amino acids Beta amino acid Aziridines Aziridine derivative Atmospheric pressure Article Amino acids
Resumen: A Ni-catalyzed reductive carboxylation of N-substituted aziridines with CO2 at atmospheric pressure is disclosed. The protocol is characterized by its mild conditions, experimental ease, and exquisite chemo- and regioselectivity pattern, thus unlocking a new catalytic blueprint to access beta-amino acids, important building blocks with considerable potential as peptidomimetics.
Áreas temáticas: Química Materiais Interdisciplinar General chemistry Farmacia Engenharias iv Engenharias iii Engenharias ii Colloid and surface chemistry Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, multidisciplinary Chemistry (miscellaneous) Chemistry (all) Chemistry Catalysis Biochemistry Astronomia / física
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: craig.day@estudiants.urv.cat
Identificador del autor: 0000-0002-6931-0280
Página final: 4954
Fecha de alta del registro: 2024-07-27
Volumen de revista: 143
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://pubs.acs.org/doi/10.1021/jacs.1c01916
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Journal Of The American Chemical Society. 143 (13): 4949-4954
Referencia de l'ítem segons les normes APA: Davies, Jacob; Janssen-Mueller, Daniel; Zimin, Dmitry P.; Day, Craig S.; Yanagi, Tomoyuki; Elfert, Jonas; Martin, Ruben; (2021). Ni-Catalyzed Carboxylation of Aziridines en Route to beta-Amino Acids. Journal Of The American Chemical Society, 143(13), 4949-4954. DOI: 10.1021/jacs.1c01916
DOI del artículo: 10.1021/jacs.1c01916
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2021
Página inicial: 4949
Tipo de publicación: Journal Publications
Repositori URV