Autor según el artículo: Davies, Jacob; Janssen-Mueller, Daniel; Zimin, Dmitry P.; Day, Craig S.; Yanagi, Tomoyuki; Elfert, Jonas; Martin, Ruben;

Departamento: Química Analítica i Química Orgànica

Autor/es de la URV: Day, Craig

Palabras clave: Unclassified drug Regioselectivity Reaction time Peptidomimetics Organic compounds Nickel compounds Nickel Limit of detection En-route Deprotection reaction Cyclization Controlled study Chemoselectivity Chemo-and regioselectivities Chemical phenomena Catalysis Carboxylation Carbon dioxide Building blockes Beta leucine Beta homotyrosine Beta homotryptophan Beta homophenylalanine Beta homoleucine Beta homoglutamate methyl ester Beta homoalanine Beta amino acids Beta amino acid Aziridines Aziridine derivative Atmospheric pressure Article Amino acids

Resumen: A Ni-catalyzed reductive carboxylation of N-substituted aziridines with CO2 at atmospheric pressure is disclosed. The protocol is characterized by its mild conditions, experimental ease, and exquisite chemo- and regioselectivity pattern, thus unlocking a new catalytic blueprint to access beta-amino acids, important building blocks with considerable potential as peptidomimetics.

Áreas temáticas: Química Materiais Interdisciplinar General chemistry Farmacia Engenharias iv Engenharias iii Engenharias ii Colloid and surface chemistry Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, multidisciplinary Chemistry (miscellaneous) Chemistry (all) Chemistry Catalysis Biochemistry Astronomia / física

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

Direcció de correo del autor: craig.day@estudiants.urv.cat

Identificador del autor: 0000-0002-6931-0280

Página final: 4954

Fecha de alta del registro: 2022-07-24

Volumen de revista: 143

Versión del articulo depositado: info:eu-repo/semantics/publishedVersion

Enlace a la fuente original: https://pubs.acs.org/doi/10.1021/jacs.1c01916

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Journal Of The American Chemical Society. 143 (13): 4949-4954

Referencia de l'ítem segons les normes APA: Davies, Jacob; Janssen-Mueller, Daniel; Zimin, Dmitry P.; Day, Craig S.; Yanagi, Tomoyuki; Elfert, Jonas; Martin, Ruben; (2021). Ni-Catalyzed Carboxylation of Aziridines en Route to beta-Amino Acids. Journal Of The American Chemical Society, 143(13), 4949-4954. DOI: 10.1021/jacs.1c01916

DOI del artículo: 10.1021/jacs.1c01916

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2021

Página inicial: 4949

Tipo de publicación: Journal Publications