Author, as appears in the article.: Davies, Jacob; Janssen-Mueller, Daniel; Zimin, Dmitry P.; Day, Craig S.; Yanagi, Tomoyuki; Elfert, Jonas; Martin, Ruben;
Department: Química Analítica i Química Orgànica
URV's Author/s: Day, Craig
Keywords: Unclassified drug Regioselectivity Reaction time Peptidomimetics Organic compounds Nickel compounds Nickel Limit of detection En-route Deprotection reaction Cyclization Controlled study Chemoselectivity Chemo-and regioselectivities Chemical phenomena Catalysis Carboxylation Carbon dioxide Building blockes Beta leucine Beta homotyrosine Beta homotryptophan Beta homophenylalanine Beta homoleucine Beta homoglutamate methyl ester Beta homoalanine Beta amino acids Beta amino acid Aziridines Aziridine derivative Atmospheric pressure Article Amino acids
Abstract: A Ni-catalyzed reductive carboxylation of N-substituted aziridines with CO2 at atmospheric pressure is disclosed. The protocol is characterized by its mild conditions, experimental ease, and exquisite chemo- and regioselectivity pattern, thus unlocking a new catalytic blueprint to access beta-amino acids, important building blocks with considerable potential as peptidomimetics.
Thematic Areas: Química Materiais Interdisciplinar General chemistry Farmacia Engenharias iv Engenharias iii Engenharias ii Colloid and surface chemistry Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, multidisciplinary Chemistry (miscellaneous) Chemistry (all) Chemistry Catalysis Biochemistry Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: craig.day@estudiants.urv.cat
Author identifier: 0000-0002-6931-0280
Last page: 4954
Record's date: 2024-07-27
Journal volume: 143
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://pubs.acs.org/doi/10.1021/jacs.1c01916
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Journal Of The American Chemical Society. 143 (13): 4949-4954
APA: Davies, Jacob; Janssen-Mueller, Daniel; Zimin, Dmitry P.; Day, Craig S.; Yanagi, Tomoyuki; Elfert, Jonas; Martin, Ruben; (2021). Ni-Catalyzed Carboxylation of Aziridines en Route to beta-Amino Acids. Journal Of The American Chemical Society, 143(13), 4949-4954. DOI: 10.1021/jacs.1c01916
Article's DOI: 10.1021/jacs.1c01916
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
First page: 4949
Publication Type: Journal Publications
Repositori URV