Articles producció científica> Química Analítica i Química Orgànica

Development of a maleic acid-based material to selectively solid-phase extract basic compounds from environmental samples

  • Dades identificatives

    Identificador: imarina:9216715
    Autors:
    Fontanals, NZohar, JBorrull, FRonka, SMarce, R M
    Resum:
    This study presents a novel mixed-mode weak cation-exchange (WCX) material. This material was prepared by means of the functionalization of a mesoporous divinylbenzene (DVB) resin with maleic acid (maleic acid-DVB), which yielded a high carboxylic moiety content resulting in WCX interactions as well as suitable specific surface area for reversed-phase interactions. After the optimization of the solid-phase extraction (SPE) protocol to enhance the selectivity of the sorbent, this material was evaluated as a novel WCX sorbent in the SPE of a group of drugs from environmental water samples. The method is based on SPE followed by liquid chromatography (LC) coupled to high resolution mass spectrometry (HRMS) with an Orbitrap analyzer, and was validated and applied for the determination of basic drugs in river, effluent and influent wastewater samples. Maleic acid-DVB sorbent yielded suitable recovery rates (57% to 89%) and an acceptable matrix effect ( < 32%) thanks to the effective washing step included when these environmental waters were loaded through the novel resin. The method was applied to different environmental water samples and some basic drugs were suitably quantified in these environmental samples. (c) 2021 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ )
  • Altres:

    Autor segons l'article: Fontanals, N; Zohar, J; Borrull, F; Ronka, S; Marce, R M
    Departament: Química Analítica i Química Orgànica
    Autor/s de la URV: Borrull Ballarín, Francesc / Fontanals Torroja, Núria / Marcé Recasens, Rosa Maria
    Paraules clau: Weak cation-exchange interactions Weak cation-exchange interaction Water sampling Water pollutants, chemical Water pollutant Water analysis Wastewater Waste-water Waste water Temperature measurement Synthesis Sorption Sorbents Sorbent Solid-phase extraction Solid-phase Solid phasis Solid phase extraction Sewage effluent Scanning electron microscopy Resins Residues Process optimization Procedures Positive ions Polymers Physical parameters Physical chemistry Phase separation Pharmaceuticals Pharmaceutical preparations Mesoporous sorbent Mass-spectrometry Mass spectrometry Maleic acids Maleic acid derivative Maleic acid Maleates Liquid chromatography Isolation and purification Extraction Exchange character Environmental water samples Environmental samples Environmental sample Effluents Drugs Drug products Drug Divinylbenzene Controlled study Chromatography, liquid Chromatography Chemistry Chemical interaction Chemical analysis Cation exchanges Basic drugs Article
    Resum: This study presents a novel mixed-mode weak cation-exchange (WCX) material. This material was prepared by means of the functionalization of a mesoporous divinylbenzene (DVB) resin with maleic acid (maleic acid-DVB), which yielded a high carboxylic moiety content resulting in WCX interactions as well as suitable specific surface area for reversed-phase interactions. After the optimization of the solid-phase extraction (SPE) protocol to enhance the selectivity of the sorbent, this material was evaluated as a novel WCX sorbent in the SPE of a group of drugs from environmental water samples. The method is based on SPE followed by liquid chromatography (LC) coupled to high resolution mass spectrometry (HRMS) with an Orbitrap analyzer, and was validated and applied for the determination of basic drugs in river, effluent and influent wastewater samples. Maleic acid-DVB sorbent yielded suitable recovery rates (57% to 89%) and an acceptable matrix effect ( < 32%) thanks to the effective washing step included when these environmental waters were loaded through the novel resin. The method was applied to different environmental water samples and some basic drugs were suitably quantified in these environmental samples. (c) 2021 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ )
    Àrees temàtiques: Zootecnia / recursos pesqueiros Química Organic chemistry Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Materiais Interdisciplinar Geociências General medicine Farmacia Engenharias ii Engenharias i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, analytical Biotecnología Biodiversidade Biochemistry Biochemical research methods Analytical chemistry
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    Adreça de correu electrònic de l'autor: nuria.fontanals@urv.cat nuria.fontanals@urv.cat rosamaria.marce@urv.cat francesc.borrull@urv.cat
    Identificador de l'autor: 0000-0002-7534-1964 0000-0002-7534-1964 0000-0002-5667-2899 0000-0003-2718-9336
    Data d'alta del registre: 2024-10-12
    Volum de revista: 1647
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://www.sciencedirect.com/science/article/pii/S0021967321002892?via%3Dihub
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Journal Of Chromatography a. 1647 (462165): 462165-
    Referència de l'ítem segons les normes APA: Fontanals, N; Zohar, J; Borrull, F; Ronka, S; Marce, R M (2021). Development of a maleic acid-based material to selectively solid-phase extract basic compounds from environmental samples. Journal Of Chromatography a, 1647(462165), 462165-. DOI: 10.1016/j.chroma.2021.462165
    DOI de l'article: 10.1016/j.chroma.2021.462165
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2021
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Analytical Chemistry,Biochemical Research Methods,Biochemistry,Chemistry, Analytical,Medicine (Miscellaneous),Organic Chemistry
    Weak cation-exchange interactions
    Weak cation-exchange interaction
    Water sampling
    Water pollutants, chemical
    Water pollutant
    Water analysis
    Wastewater
    Waste-water
    Waste water
    Temperature measurement
    Synthesis
    Sorption
    Sorbents
    Sorbent
    Solid-phase extraction
    Solid-phase
    Solid phasis
    Solid phase extraction
    Sewage effluent
    Scanning electron microscopy
    Resins
    Residues
    Process optimization
    Procedures
    Positive ions
    Polymers
    Physical parameters
    Physical chemistry
    Phase separation
    Pharmaceuticals
    Pharmaceutical preparations
    Mesoporous sorbent
    Mass-spectrometry
    Mass spectrometry
    Maleic acids
    Maleic acid derivative
    Maleic acid
    Maleates
    Liquid chromatography
    Isolation and purification
    Extraction
    Exchange character
    Environmental water samples
    Environmental samples
    Environmental sample
    Effluents
    Drugs
    Drug products
    Drug
    Divinylbenzene
    Controlled study
    Chromatography, liquid
    Chromatography
    Chemistry
    Chemical interaction
    Chemical analysis
    Cation exchanges
    Basic drugs
    Article
    Zootecnia / recursos pesqueiros
    Química
    Organic chemistry
    Nutrição
    Medicine (miscellaneous)
    Medicina veterinaria
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Geociências
    General medicine
    Farmacia
    Engenharias ii
    Engenharias i
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Ciência de alimentos
    Chemistry, analytical
    Biotecnología
    Biodiversidade
    Biochemistry
    Biochemical research methods
    Analytical chemistry
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