Articles producció científica> Enginyeria Electrònica, Elèctrica i Automàtica

Oligonucleotic Probes and Immunosensors Based on Nanoporous Anodic Alumina for Screening of Diseases

  • Dades identificatives

    Identificador: imarina:9249015
    Autors:
    Xifre-Perez, ElisabetFerre-Borrull, JosepMarsal, Lluis F
    Resum:
    This paper is an overview of the recent advances in nanoporous anodic alumina sensing platforms based on the interaction of oligonucleotides and antibodies with bioelements (e.g., virus, bacteria, or biomarkers) that can cause or identify diseases. Nanoporous alumina is the common platform material for all these sensing devices that have an enormous potential for the next-generation bioanalytical systems. Nanoporous alumina is a cost-effective material with morphological flexibility that provides high sensitivity to the sensing systems due to its large surface-to-volume ratio. Immunosensors transduce the signal produced by the specific antibody-antigen interaction. They are widely used for clinical analysis due to the high selectivity and sensitivity of their immunoreaction, transduced by different methods (electrochemical, optical, piezoelectric, etc). Another important, outstanding and more recently type of biosensors are based on the oligonucleotic functionalization of nanoporous alumina. Oligonucleotides can bind to a wide variety of elements (small organic molecules, proteins, or cells) with high selectivity, specificity, and affinity, even higher to those of antibodies. The basic concepts and mechanisms of their sensing methods for health care biosensing are introduced. Their transduction methods and great potential applications will be evaluated and classified in detail, together with a discussion of possible future trends.
  • Altres:

    Autor segons l'article: Xifre-Perez, Elisabet; Ferre-Borrull, Josep; Marsal, Lluis F
    Departament: Enginyeria Electrònica, Elèctrica i Automàtica
    Autor/s de la URV: Ferré Borrull, José / Marsal Garví, Luis Francisco / Xifré Pérez, Elisabet
    Paraules clau: Ultrasensitive detection Surface-plasmon resonance Pulse anodization Porous alumina Photonic crystals Oligonucleotides Nanoporous anodic alumina Nanoparticles enhance Immunosensors Health Free optical-detection Free dna biosensor Electrochemical nanobiosensor Distributed-bragg-reflector Biosensors Aptamers Antibodies
    Resum: This paper is an overview of the recent advances in nanoporous anodic alumina sensing platforms based on the interaction of oligonucleotides and antibodies with bioelements (e.g., virus, bacteria, or biomarkers) that can cause or identify diseases. Nanoporous alumina is the common platform material for all these sensing devices that have an enormous potential for the next-generation bioanalytical systems. Nanoporous alumina is a cost-effective material with morphological flexibility that provides high sensitivity to the sensing systems due to its large surface-to-volume ratio. Immunosensors transduce the signal produced by the specific antibody-antigen interaction. They are widely used for clinical analysis due to the high selectivity and sensitivity of their immunoreaction, transduced by different methods (electrochemical, optical, piezoelectric, etc). Another important, outstanding and more recently type of biosensors are based on the oligonucleotic functionalization of nanoporous alumina. Oligonucleotides can bind to a wide variety of elements (small organic molecules, proteins, or cells) with high selectivity, specificity, and affinity, even higher to those of antibodies. The basic concepts and mechanisms of their sensing methods for health care biosensing are introduced. Their transduction methods and great potential applications will be evaluated and classified in detail, together with a discussion of possible future trends.
    Àrees temàtiques: Mechanics of materials Materials science, multidisciplinary Materials science (miscellaneous) Materials science (all) Industrial and manufacturing engineering General materials science
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    Adreça de correu electrònic de l'autor: josep.ferre@urv.cat elisabet.xifre@urv.cat lluis.marsal@urv.cat
    Identificador de l'autor: 0000-0002-5210-5133 0000-0001-6072-9889 0000-0002-5976-1408
    Data d'alta del registre: 2024-10-12
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://onlinelibrary.wiley.com/doi/full/10.1002/admt.202101591
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Advanced Materials Technologies. 7 (9): 2101591-
    Referència de l'ítem segons les normes APA: Xifre-Perez, Elisabet; Ferre-Borrull, Josep; Marsal, Lluis F (2022). Oligonucleotic Probes and Immunosensors Based on Nanoporous Anodic Alumina for Screening of Diseases. Advanced Materials Technologies, 7(9), 2101591-. DOI: 10.1002/admt.202101591
    DOI de l'article: 10.1002/admt.202101591
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2022
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Industrial and Manufacturing Engineering,Materials Science (Miscellaneous),Materials Science, Multidisciplinary,Mechanics of Materials
    Ultrasensitive detection
    Surface-plasmon resonance
    Pulse anodization
    Porous alumina
    Photonic crystals
    Oligonucleotides
    Nanoporous anodic alumina
    Nanoparticles enhance
    Immunosensors
    Health
    Free optical-detection
    Free dna biosensor
    Electrochemical nanobiosensor
    Distributed-bragg-reflector
    Biosensors
    Aptamers
    Antibodies
    Mechanics of materials
    Materials science, multidisciplinary
    Materials science (miscellaneous)
    Materials science (all)
    Industrial and manufacturing engineering
    General materials science
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