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Oligonucleotic Probes and Immunosensors Based on Nanoporous Anodic Alumina for Screening of Diseases

  • Datos identificativos

    Identificador: imarina:9249015
    Autores:
    Xifre-Perez, ElisabetFerre-Borrull, JosepMarsal, Lluis F
    Resumen:
    This paper is an overview of the recent advances in nanoporous anodic alumina sensing platforms based on the interaction of oligonucleotides and antibodies with bioelements (e.g., virus, bacteria, or biomarkers) that can cause or identify diseases. Nanoporous alumina is the common platform material for all these sensing devices that have an enormous potential for the next-generation bioanalytical systems. Nanoporous alumina is a cost-effective material with morphological flexibility that provides high sensitivity to the sensing systems due to its large surface-to-volume ratio. Immunosensors transduce the signal produced by the specific antibody-antigen interaction. They are widely used for clinical analysis due to the high selectivity and sensitivity of their immunoreaction, transduced by different methods (electrochemical, optical, piezoelectric, etc). Another important, outstanding and more recently type of biosensors are based on the oligonucleotic functionalization of nanoporous alumina. Oligonucleotides can bind to a wide variety of elements (small organic molecules, proteins, or cells) with high selectivity, specificity, and affinity, even higher to those of antibodies. The basic concepts and mechanisms of their sensing methods for health care biosensing are introduced. Their transduction methods and great potential applications will be evaluated and classified in detail, together with a discussion of possible future trends.
  • Otros:

    Autor según el artículo: Xifre-Perez, Elisabet; Ferre-Borrull, Josep; Marsal, Lluis F
    Departamento: Enginyeria Electrònica, Elèctrica i Automàtica
    Autor/es de la URV: Ferré Borrull, José / Marsal Garví, Luis Francisco / Xifré Pérez, Elisabet
    Palabras clave: Ultrasensitive detection Surface-plasmon resonance Pulse anodization Porous alumina Photonic crystals Oligonucleotides Nanoporous anodic alumina Nanoparticles enhance Immunosensors Health Free optical-detection Free dna biosensor Electrochemical nanobiosensor Distributed-bragg-reflector Biosensors Aptamers Antibodies
    Resumen: This paper is an overview of the recent advances in nanoporous anodic alumina sensing platforms based on the interaction of oligonucleotides and antibodies with bioelements (e.g., virus, bacteria, or biomarkers) that can cause or identify diseases. Nanoporous alumina is the common platform material for all these sensing devices that have an enormous potential for the next-generation bioanalytical systems. Nanoporous alumina is a cost-effective material with morphological flexibility that provides high sensitivity to the sensing systems due to its large surface-to-volume ratio. Immunosensors transduce the signal produced by the specific antibody-antigen interaction. They are widely used for clinical analysis due to the high selectivity and sensitivity of their immunoreaction, transduced by different methods (electrochemical, optical, piezoelectric, etc). Another important, outstanding and more recently type of biosensors are based on the oligonucleotic functionalization of nanoporous alumina. Oligonucleotides can bind to a wide variety of elements (small organic molecules, proteins, or cells) with high selectivity, specificity, and affinity, even higher to those of antibodies. The basic concepts and mechanisms of their sensing methods for health care biosensing are introduced. Their transduction methods and great potential applications will be evaluated and classified in detail, together with a discussion of possible future trends.
    Áreas temáticas: Mechanics of materials Materials science, multidisciplinary Materials science (miscellaneous) Materials science (all) Industrial and manufacturing engineering General materials science
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    Direcció de correo del autor: josep.ferre@urv.cat elisabet.xifre@urv.cat lluis.marsal@urv.cat
    Identificador del autor: 0000-0002-5210-5133 0000-0001-6072-9889 0000-0002-5976-1408
    Fecha de alta del registro: 2024-10-12
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Enlace a la fuente original: https://onlinelibrary.wiley.com/doi/full/10.1002/admt.202101591
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referencia al articulo segun fuente origial: Advanced Materials Technologies. 7 (9): 2101591-
    Referencia de l'ítem segons les normes APA: Xifre-Perez, Elisabet; Ferre-Borrull, Josep; Marsal, Lluis F (2022). Oligonucleotic Probes and Immunosensors Based on Nanoporous Anodic Alumina for Screening of Diseases. Advanced Materials Technologies, 7(9), 2101591-. DOI: 10.1002/admt.202101591
    DOI del artículo: 10.1002/admt.202101591
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2022
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Industrial and Manufacturing Engineering,Materials Science (Miscellaneous),Materials Science, Multidisciplinary,Mechanics of Materials
    Ultrasensitive detection
    Surface-plasmon resonance
    Pulse anodization
    Porous alumina
    Photonic crystals
    Oligonucleotides
    Nanoporous anodic alumina
    Nanoparticles enhance
    Immunosensors
    Health
    Free optical-detection
    Free dna biosensor
    Electrochemical nanobiosensor
    Distributed-bragg-reflector
    Biosensors
    Aptamers
    Antibodies
    Mechanics of materials
    Materials science, multidisciplinary
    Materials science (miscellaneous)
    Materials science (all)
    Industrial and manufacturing engineering
    General materials science
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