Autor segons l'article: Boutureira, Omar; Bernardes, Goncalo J L
Departament: Química Analítica i Química Orgànica
Autor/s de la URV: Boutureira Martín, Omar
Paraules clau: Transition elements Thiol-ene reaction Site-specific conjugation Selective cysteine modification Proteins Pictet-spengler ligation Photoclick-chemistry Mediated protein Humans Directed tosyl chemistry Cross-metathesis Click chemistry Chemistry techniques, synthetic Azide-alkyne cycloaddition Animals Amino acids
Resum: Protein chemical modification is a problem-solving technique in research and technology. Modifications also occur in natural deteriorations. Generally these modifications are with the most reactive side chains and are predominantly oxidations, reductions, and nucleophilic and electrophilic substitutions. Deteriorations include peptide bond scissions, racemizations, β-eliminations, and formation of products by the reaction of proteins with added chemicals. Proteins are modified intentionally for structure-function relationship studies or for development of new and improved products. Although appearing quite varied, the techniques used in pharmacological, food and feed, or other industrial areas differ more operationally than from major differences in the levels of chemical sophistication that are used.
Àrees temàtiques: Química Materiais General medicine General chemistry Farmacia Engenharias iii Engenharias ii Ciências biológicas ii Ciências biológicas i Ciência de alimentos Chemistry, multidisciplinary Chemistry (miscellaneous) Chemistry (all) Chemistry Biotecnología
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: omar.boutureira@urv.cat
Identificador de l'autor: 0000-0002-0768-8309
Data d'alta del registre: 2024-11-30
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Chemical Reviews. 115 (5): 2174-2195
Referència de l'ítem segons les normes APA: Boutureira, Omar; Bernardes, Goncalo J L (2015). Advances in Chemical Protein Modification. Chemical Reviews, 115(5), 2174-2195. DOI: 10.1021/cr500399p
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2015
Tipus de publicació: Journal Publications