Author, as appears in the article.: Boutureira, Omar; Bernardes, Goncalo J L
Department: Química Analítica i Química Orgànica
URV's Author/s: Boutureira Martín, Omar
Keywords: Transition elements Thiol-ene reaction Site-specific conjugation Selective cysteine modification Proteins Pictet-spengler ligation Photoclick-chemistry Mediated protein Humans Directed tosyl chemistry Cross-metathesis Click chemistry Chemistry techniques, synthetic Azide-alkyne cycloaddition Animals Amino acids
Abstract: Protein chemical modification is a problem-solving technique in research and technology. Modifications also occur in natural deteriorations. Generally these modifications are with the most reactive side chains and are predominantly oxidations, reductions, and nucleophilic and electrophilic substitutions. Deteriorations include peptide bond scissions, racemizations, β-eliminations, and formation of products by the reaction of proteins with added chemicals. Proteins are modified intentionally for structure-function relationship studies or for development of new and improved products. Although appearing quite varied, the techniques used in pharmacological, food and feed, or other industrial areas differ more operationally than from major differences in the levels of chemical sophistication that are used.
Thematic Areas: Química Materiais General medicine General chemistry Farmacia Engenharias iii Engenharias ii Ciências biológicas ii Ciências biológicas i Ciência de alimentos Chemistry, multidisciplinary Chemistry (miscellaneous) Chemistry (all) Chemistry Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: omar.boutureira@urv.cat
Author identifier: 0000-0002-0768-8309
Record's date: 2024-11-30
Papper version: info:eu-repo/semantics/publishedVersion
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Chemical Reviews. 115 (5): 2174-2195
APA: Boutureira, Omar; Bernardes, Goncalo J L (2015). Advances in Chemical Protein Modification. Chemical Reviews, 115(5), 2174-2195. DOI: 10.1021/cr500399p
Entity: Universitat Rovira i Virgili
Journal publication year: 2015
Publication Type: Journal Publications