Articles producció científica> Química Analítica i Química Orgànica

Topological Defects in Hyperbranched Glycopolymers Enhance Binding to Lectins

  • Identification data

    Identifier: imarina:5131923
    Handle: https://hdl.handle.net/20.500.11797/imarina5131923
    Authors:
    Salvado, MiriamReina, Jose JRojo, JavierCastillon, SergioBoutureira, Omar
    Abstract:
    Central scaffold topology and carbohydrate density are important features in determining both the binding mechanism and potency of synthetic multivalent, polydisperse vs. monodisperse carbohydrate systems to a model plant toxin (RCA120). We found lower densities of protein receptors favour the use of heterogeneous, polydisperse glycoconjugate presentations as determined by surface plasmon resonance (SPR) and dynamic light scattering (DLS).

  • Others:

    Author, as appears in the article.: Salvado, Miriam; Reina, Jose J; Rojo, Javier; Castillon, Sergio; Boutureira, Omar
    Department: Química Analítica i Química Orgànica
    URV's Author/s: Boutureira Martín, Omar / Castillón Miranda, Sergio / Salvadó Artells, Marçal
    Keywords: Surface plasmon resonance Ricinus communis agglutinin-1 Protein binding Polymers Plant lectins Multivalency Molecular recognition Lectins Glycoconjugates Dynamic light scattering Dendrimers Carbohydrates molecular recognition glycoconjugates dendrimers carbohydrates
    Abstract: Central scaffold topology and carbohydrate density are important features in determining both the binding mechanism and potency of synthetic multivalent, polydisperse vs. monodisperse carbohydrate systems to a model plant toxin (RCA120). We found lower densities of protein receptors favour the use of heterogeneous, polydisperse glycoconjugate presentations as determined by surface plasmon resonance (SPR) and dynamic light scattering (DLS).
    Thematic Areas: Química Organic chemistry Medicina i Materiais Interdisciplinar General medicine General chemistry Farmacia Engenharias iii Engenharias ii Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Chemistry, multidisciplinary Chemistry (miscellaneous) Chemistry (all) Chemistry Catalysis Biotecnología Biodiversidade Astronomia / física
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: omar.boutureira@urv.cat m.salvado@urv.cat sergio.castillon@urv.cat
    Author identifier: 0000-0002-0768-8309 0000-0002-9399-6649 0000-0002-0690-7549
    Record's date: 2024-11-30
    Papper version: info:eu-repo/semantics/acceptedVersion
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Chemistry-A European Journal. 23 (62): 15790-15794
    APA: Salvado, Miriam; Reina, Jose J; Rojo, Javier; Castillon, Sergio; Boutureira, Omar (2017). Topological Defects in Hyperbranched Glycopolymers Enhance Binding to Lectins. Chemistry-A European Journal, 23(62), 15790-15794. DOI: 10.1002/chem.201703432
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2017
    Publication Type: Journal Publications

  • Keywords:

    Catalysis,Chemistry,Chemistry (Miscellaneous),Chemistry, Multidisciplinary,Organic Chemistry
    Surface plasmon resonance
    Ricinus communis agglutinin-1
    Protein binding
    Polymers
    Plant lectins
    Multivalency
    Molecular recognition
    Lectins
    Glycoconjugates
    Dynamic light scattering
    Dendrimers
    Carbohydrates
    molecular recognition
    glycoconjugates
    dendrimers
    carbohydrates
    Química
    Organic chemistry
    Medicina i
    Materiais
    Interdisciplinar
    General medicine
    General chemistry
    Farmacia
    Engenharias iii
    Engenharias ii
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Chemistry, multidisciplinary
    Chemistry (miscellaneous)
    Chemistry (all)
    Chemistry
    Catalysis
    Biotecnología
    Biodiversidade
    Astronomia / física

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