Hypercrosslinked particles for the extraction of sweeteners using dispersive solid-phase extraction from environmental samples

Identifier:  imarina:5131933

Handle: https://hdl.handle.net/20.500.11797/imarina5131933

Authors:  Lakade, SS; Zhou, Q; Li, AM; Borrull, F; Fontanals, N; Marcé, RM

Abstract:
This work presents a new extraction material, namely, Q-100, based on hyper-crosslinked magnetic particles, which was tested in dispersive solid-phase extrac-tion for a group of sweeteners from environmental samples. The hypercrosslinkedQ-100 magnetic particles had the advantage of suitable pore size distribution andhigh surface area, and showed good retention behavior toward sweeteners. Di¿erentdispersive solid-phase extraction parameters such as amount of magnetic particles orextraction time were optimized. Under optimum conditions, Q-100 showed suitableapparent recovery, ranging in the case of river water sample from 21 to 88% for allthe sweeteners, except for alitame (12%). The validated method based on dispersivesolid-phase extraction using Q-100 followed by liquid chromatography with tandemmass spectrometry provided good linearity and limits of quanti¿cation between 0.01and 0.1 ¿g/L. The method was applied to analyze samples from river water and e¿u-ent wastewater, and four sweeteners (acesulfame, saccharin, cyclamate, and sucralose)were found in both types of sample.