Articles producció científica> Medicina i Cirurgia

Case-Control Analysis of the Impact of Anemia on Quality of Life in Patients with Cancer: A Qca Study Analysis

  • Identification data

    Identifier: imarina:9231550
    Handle: http://hdl.handle.net/20.500.11797/imarina9231550
  • Authors:

    Barca-Hernando, Maria
    Munoz-Martin, Andres J.
    Rios-Herranz, Eduardo
    Garcia-Escobar, Ignacio
    Beato, Carmen
    Font, Carme
    Oncala-Sibajas, Estefania
    Revuelta-Rodriguez, Alfonso
    Areses, Maria Carmen
    Rivas-Jimenez, Victor
    Ballaz-Quincoces, Aitor
    Moreno-Santos, Maria Angeles
    Lopez-Saez, Juan-Bosco
    Gallego-Gallego, Iria
    Elias-Hernandez, Teresa
    Asensio-Cruz, Maria Isabel
    Chasco-Eguilaz, Leyre
    Garcia-Gonzalez, Gonzalo
    Estevez-Garcia, Purificacion
    Marin-Barrera, Lucia
    Otero-Candelera, Remedios
    Lopez-Ruz, Sergio
    Lima-Alvarez, Jorge
    Sanchez-Diaz, Jose Maria
    Real-Dominguez, Macarena
    Borrego-Delgado, Maria Carmen
    Marin-Romero, Samira
    Jara-Palomares, Luis
  • Others:

    Author, as appears in the article.: Barca-Hernando, Maria; Munoz-Martin, Andres J.; Rios-Herranz, Eduardo; Garcia-Escobar, Ignacio; Beato, Carmen; Font, Carme; Oncala-Sibajas, Estefania; Revuelta-Rodriguez, Alfonso; Areses, Maria Carmen; Rivas-Jimenez, Victor; Ballaz-Quincoces, Aitor; Moreno-Santos, Maria Angeles; Lopez-Saez, Juan-Bosco; Gallego-Gallego, Iria; Elias-Hernandez, Teresa; Asensio-Cruz, Maria Isabel; Chasco-Eguilaz, Leyre; Garcia-Gonzalez, Gonzalo; Estevez-Garcia, Purificacion; Marin-Barrera, Lucia; Otero-Candelera, Remedios; Lopez-Ruz, Sergio; Lima-Alvarez, Jorge; Sanchez-Diaz, Jose Maria; Real-Dominguez, Macarena; Borrego-Delgado, Maria Carmen; Marin-Romero, Samira; Jara-Palomares, Luis;
    Department: Medicina i Cirurgia
    URV's Author/s: PORRAS LEDANTES, JOSE ANTONIO
    Keywords: Anaemia Chemotherapy Double-blind Eortc qlq-c30 Epoetin-alpha Fatigue Functional assessment Lung-cancer Neoplasm Outcomes Prevalence Quality of life Symptoms
    Abstract: Simple SummaryThe impact of anemia on the quality of life (QoL) in cancer patients has been studied previously; however, the cut-off point used to define anemia differed among studies, thus providing inconsistent results. Therefore, we analysed the clinical impact of anemia on QoL using the same cut-off point for hemoglobin level to define anemia as that used in ESMO clinical practice guidelines. This post-hoc analysis aimed to determine the impact of anemia on QoL in cancer patients through the European Organization for Research and Treatment of Cancer Quality of life questionnaire version 3.0 (EORTC QLQ-C30) and Euro QoL 5-dimension 3-level (EQ-5D-3L) questionnaire. We found that cancer patients with anemia had significantly worse QoL in clinical terms. In addition, anemic patients had more pronounced symptoms than those in non-anemic patients.Anemia is a common condition in cancer patients and is associated with a wide variety of symptoms that impair quality of life (QoL). However, exactly how anemia affects QoL in cancer patients is unclear because of the inconsistencies in its definition in previous reports. We aimed to examine the clinical impact of anemia on the QoL of cancer patients using specific questionnaires. We performed a post-hoc analysis of a multicenter, prospective, case-control study. We included patients with cancer with (cases) or without (controls) anemia. Participants completed the European Organization for Research and Treatment of Cancer Quality of Life questionnaire version 3.0 (EORTC QLQ-C30) and Euro QoL 5-dimension 3-level (EQ-5D-3L) questionnaire. Statistically significant and clinically relevant differences in the global health status were examined. From 2015 to 2018, 365 patients were included (90 cases and 275 controls). We found minimally important differences in global health status according to the EORTC QLQ-C30 questionnaire (case vs. controls: 45.6 vs. 58%, respectively; mean difference: -12.4, p < 0.001). Regarding symptoms, cancer patients with anemia had more pronounced symptoms in six out of nine scales in comparison with those without anemia. In conclusion, cancer patients with anemia had a worse QoL both clinically and statistically.
    Thematic Areas: Cancer research Medicina iii Oncology
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: joseantonio.porras@urv.cat
    Author identifier: 0000-0001-6418-1822 0000-0002-2265-1221
    Record's date: 2021-11-21
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.mdpi.com/2072-6694/13/11/2517
    Papper original source: Cancers. 13 (11):
    APA: Barca-Hernando, Maria; Munoz-Martin, Andres J.; Rios-Herranz, Eduardo; Garcia-Escobar, Ignacio; Beato, Carmen; Font, Carme; Oncala-Sibajas, Estefania; (2021). Case-Control Analysis of the Impact of Anemia on Quality of Life in Patients with Cancer: A Qca Study Analysis. Cancers, 13(11), -. DOI: 10.3390/cancers13112517
    Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.3390/cancers13112517
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications
  • Keywords:

    Cancer Research,Oncology
    Anaemia
    Chemotherapy
    Double-blind
    Eortc qlq-c30
    Epoetin-alpha
    Fatigue
    Functional assessment
    Lung-cancer
    Neoplasm
    Outcomes
    Prevalence
    Quality of life
    Symptoms
    Cancer research
    Medicina iii
    Oncology
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