Articles producció científica> Química Analítica i Química Orgànica

Bench-Stable Electrophilic Reagents for the Direct Di- and Trifluoroethylthiolation of Indoles

  • Identification data

    Identifier: imarina:9325555
    Handle: https://hdl.handle.net/20.500.11797/imarina9325555
    Authors:
    Casasus, PaulaMestre, JordiBernus, MiguelCastillon, SergioBoutureira, Omar
    Abstract:
    Two saccharine-based electrophilic reagents were developed for the direct introduction of SCH2CF3 and SCH2CF2H motifs via a C−S bond forming reaction. Their large-scale preparation and reactivity performance has been carefully examined, enabling access to a series of indoles through open-flask reactions. Sulfone and sulfoxide analogs (S(O)nCH2RF, n=1,2) are also accessible by sequential oxidation reactions. (Figure presented.).

  • Others:

    Author, as appears in the article.: Casasus, Paula; Mestre, Jordi; Bernus, Miguel; Castillon, Sergio; Boutureira, Omar
    Department: Química Analítica i Química Orgànica
    URV's Author/s: Bernús Pérez, Miguel / Boutureira Martín, Omar / Casasús Pascua, Paula / Castillón Miranda, Sergio / Mestre Ventura, Jordi
    Keywords: Indoles Fluoroalkylthiolation Fluorine Electrophilic reagents Chalcogens indoles fluoroalkylthiolation fluorine electrophilic reagents catalysis
    Abstract: Two saccharine-based electrophilic reagents were developed for the direct introduction of SCH2CF3 and SCH2CF2H motifs via a C−S bond forming reaction. Their large-scale preparation and reactivity performance has been carefully examined, enabling access to a series of indoles through open-flask reactions. Sulfone and sulfoxide analogs (S(O)nCH2RF, n=1,2) are also accessible by sequential oxidation reactions. (Figure presented.).
    Thematic Areas: Química Organic chemistry Materiais Engenharias iv Engenharias ii Ciências biológicas ii Ciência de alimentos Chemistry, organic Chemistry, applied Catalysis Biodiversidade Astronomia / física
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: paula.casasus@urv.cat miguel.bernus@urv.cat omar.boutureira@urv.cat miguel.bernus@urv.cat miguel.bernus@urv.cat sergio.castillon@urv.cat
    Author identifier: 0000-0003-0302-0720 0000-0002-0768-8309 0000-0003-0302-0720 0000-0003-0302-0720 0000-0002-0690-7549
    Record's date: 2024-11-30
    Papper version: info:eu-repo/semantics/publishedVersion
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Advanced Synthesis & Catalysis. 365 (20): 3438-3443
    APA: Casasus, Paula; Mestre, Jordi; Bernus, Miguel; Castillon, Sergio; Boutureira, Omar (2023). Bench-Stable Electrophilic Reagents for the Direct Di- and Trifluoroethylthiolation of Indoles. Advanced Synthesis & Catalysis, 365(20), 3438-3443. DOI: 10.1002/adsc.202300586
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2023
    Publication Type: Journal Publications

  • Keywords:

    Catalysis,Chemistry, Applied,Chemistry, Organic,Organic Chemistry
    Indoles
    Fluoroalkylthiolation
    Fluorine
    Electrophilic reagents
    Chalcogens
    indoles
    fluoroalkylthiolation
    fluorine
    electrophilic reagents
    catalysis
    Química
    Organic chemistry
    Materiais
    Engenharias iv
    Engenharias ii
    Ciências biológicas ii
    Ciência de alimentos
    Chemistry, organic
    Chemistry, applied
    Catalysis
    Biodiversidade
    Astronomia / física

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