Author, as appears in the article.: Casasus, P; Mestre, J; Bernus, M; Castillon, S; Boutureira, O
Department: Química Analítica i Química Orgànica
URV's Author/s: Boutureira Martín, Omar / Castillón Miranda, Sergio
Keywords: Indoles Fluoroalkylthiolation Fluorine Electrophilic reagents Chalcogens indoles fluoroalkylthiolation fluorine electrophilic reagents catalysis
Abstract: Two saccharine-based electrophilic reagents were developed for the direct introduction of SCH2CF3 and SCH2CF2H motifs via a C−S bond forming reaction. Their large-scale preparation and reactivity performance has been carefully examined, enabling access to a series of indoles through open-flask reactions. Sulfone and sulfoxide analogs (S(O)nCH2RF, n=1,2) are also accessible by sequential oxidation reactions. (Figure presented.).
Thematic Areas: Química Organic chemistry Materiais Engenharias iv Engenharias ii Ciências biológicas ii Ciência de alimentos Chemistry, organic Chemistry, applied Catalysis Biodiversidade Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: omar.boutureira@urv.cat sergio.castillon@urv.cat
Author identifier: 0000-0002-0768-8309 0000-0002-0690-7549
Record's date: 2024-08-03
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://onlinelibrary.wiley.com/doi/full/10.1002/adsc.202300586
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Advanced Synthesis & Catalysis. 365 (20): 3438-3443
APA: Casasus, P; Mestre, J; Bernus, M; Castillon, S; Boutureira, O (2023). Bench-Stable Electrophilic Reagents for the Direct Di- and Trifluoroethylthiolation of Indoles. Advanced Synthesis & Catalysis, 365(20), 3438-3443. DOI: 10.1002/adsc.202300586
Article's DOI: 10.1002/adsc.202300586
Entity: Universitat Rovira i Virgili
Journal publication year: 2023
Publication Type: Journal Publications
Repositori URV