Articles producció científica> Química Analítica i Química Orgànica

Bench-Stable Electrophilic Reagents for the Direct Di- and Trifluoroethylthiolation of Indoles

  • Datos identificativos

    Identificador: imarina:9325555
    Autores:
    Casasus, PaulaMestre, JordiBernus, MiguelCastillon, SergioBoutureira, Omar
    Resumen:
    Two saccharine-based electrophilic reagents were developed for the direct introduction of SCH2CF3 and SCH2CF2H motifs via a C−S bond forming reaction. Their large-scale preparation and reactivity performance has been carefully examined, enabling access to a series of indoles through open-flask reactions. Sulfone and sulfoxide analogs (S(O)nCH2RF, n=1,2) are also accessible by sequential oxidation reactions. (Figure presented.).
  • Otros:

    Autor según el artículo: Casasus, Paula; Mestre, Jordi; Bernus, Miguel; Castillon, Sergio; Boutureira, Omar
    Departamento: Química Analítica i Química Orgànica
    Autor/es de la URV: Bernús Pérez, Miguel / Boutureira Martín, Omar / Casasús Pascua, Paula / Castillón Miranda, Sergio / Mestre Ventura, Jordi
    Palabras clave: Indoles Fluoroalkylthiolation Fluorine Electrophilic reagents Chalcogens indoles fluoroalkylthiolation fluorine electrophilic reagents catalysis
    Resumen: Two saccharine-based electrophilic reagents were developed for the direct introduction of SCH2CF3 and SCH2CF2H motifs via a C−S bond forming reaction. Their large-scale preparation and reactivity performance has been carefully examined, enabling access to a series of indoles through open-flask reactions. Sulfone and sulfoxide analogs (S(O)nCH2RF, n=1,2) are also accessible by sequential oxidation reactions. (Figure presented.).
    Áreas temáticas: Química Organic chemistry Materiais Engenharias iv Engenharias ii Ciências biológicas ii Ciência de alimentos Chemistry, organic Chemistry, applied Catalysis Biodiversidade Astronomia / física
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    Direcció de correo del autor: paula.casasus@urv.cat miguel.bernus@urv.cat omar.boutureira@urv.cat miguel.bernus@urv.cat miguel.bernus@urv.cat sergio.castillon@urv.cat
    Identificador del autor: 0000-0003-0302-0720 0000-0002-0768-8309 0000-0003-0302-0720 0000-0003-0302-0720 0000-0002-0690-7549
    Fecha de alta del registro: 2024-11-30
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referencia al articulo segun fuente origial: Advanced Synthesis & Catalysis. 365 (20): 3438-3443
    Referencia de l'ítem segons les normes APA: Casasus, Paula; Mestre, Jordi; Bernus, Miguel; Castillon, Sergio; Boutureira, Omar (2023). Bench-Stable Electrophilic Reagents for the Direct Di- and Trifluoroethylthiolation of Indoles. Advanced Synthesis & Catalysis, 365(20), 3438-3443. DOI: 10.1002/adsc.202300586
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2023
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Catalysis,Chemistry, Applied,Chemistry, Organic,Organic Chemistry
    Indoles
    Fluoroalkylthiolation
    Fluorine
    Electrophilic reagents
    Chalcogens
    indoles
    fluoroalkylthiolation
    fluorine
    electrophilic reagents
    catalysis
    Química
    Organic chemistry
    Materiais
    Engenharias iv
    Engenharias ii
    Ciências biológicas ii
    Ciência de alimentos
    Chemistry, organic
    Chemistry, applied
    Catalysis
    Biodiversidade
    Astronomia / física
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