Author, as appears in the article.: Iqbal, Sajid; Abu Jayyab, Abdulrahim; Alrashdi, Ayah Mohammad; Shujauddin, Syed; Clua-Espuny, Josep Lluis; Reverte-Villarroya, Silvia
Department: Infermeria
URV's Author/s: Reverté Villarroya, Silvia
Keywords: Adults Ag Beta-cell function C-peptide Children Classification Diabetes mellitus Diagnosis Help Mellitus Pilot Predictive ability of c-peptide Prevalence Type 1 diabetes Type 2 diabete Type 2 diabetes Β-cell function
Abstract: Purpose: We aimed to investigate the predictive potential of plasma connecting peptide (C-peptide) in differentiating type 1 diabetes (T1D) from type 2 diabetes (T2D) and to inform evidence-based diabetes classification criteria. Methods: A retrospective review was performed of all the patients with diabetes visiting an outpatient diabetology, endocrinology, general practice and family medicine tertiary health care center between January 2016 and December 2021. Findings: Two hundred twelve individuals with diabetes were included, 85 (44.8%) with T1D and 127 (55.2%) with T2D. Mean (SD) age at diagnosis was 35.9 (15.1) years, and 112 (52.8%) men. Median (interquartile range [IQR]) duration of diabetes was 3.8 (3.0-4.5) years (T1D, 3.9 [3.5-4.6]; T2D, 3.4 [2.4-4.4]; P = 0.001). Body mass index was < 18.5 kg/m2 2 in 5 (2.5%) individuals (T1D, 5; T2D, none), 18.5 to < 25 kg/m2 2 in 57 (28.5%) (T1D, 32; T2D, 25), 25 to < 30 kg/m2 2 in 58 (29%) (T1D, 28; T2D, 30), and > 30 kg/m2 2 in 80 (40.0%) (T1D, 20; T2D, 60). Median (IQR) glycosylated hemoglobin was 7.4% (6.7%-8.5%) (T1D, 8.3% [7.2%-9.9%]; T2D, 7% [6.3%- 7.6%]; P = 0.0001). Median (IQR) C-peptide concentration was 0.59 nmol/L (0.01-1.14 nmol/L) (T1D, 0.01 nmol/L [0.003-0.05 nmol/L]; T2D, 1.03 nmol/L [0.70-1.44 nmol/L]; P = 0.0001). C-peptide concentration of
Thematic Areas: Ciências biológicas i Ciências biológicas ii Engenharias iv Farmacia General medicine Interdisciplinar Medicina i Medicina ii Medicina iii Pharmacology Pharmacology & pharmacy Pharmacology (medical) Saúde coletiva
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: silvia.reverte@urv.cat
Author identifier: 0000-0002-2052-9978
Record's date: 2024-10-05
Papper version: info:eu-repo/semantics/publishedVersion
Papper original source: Clinical Therapeutics. 46 (9): 696-701
APA: Iqbal, Sajid; Abu Jayyab, Abdulrahim; Alrashdi, Ayah Mohammad; Shujauddin, Syed; Clua-Espuny, Josep Lluis; Reverte-Villarroya, Silvia (2024). The Predictive Potential of C-Peptide in Differentiating Type 1 Diabetes From Type 2 Diabetes in an Outpatient Population in Abu Dhabi. Clinical Therapeutics, 46(9), 696-701. DOI: 10.1016/j.clinthera.2024.07.002
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Entity: Universitat Rovira i Virgili
Journal publication year: 2024
Publication Type: Journal Publications
Repositori URV