Autor según el artículo: Iqbal, Sajid; Abu Jayyab, Abdulrahim; Alrashdi, Ayah Mohammad; Shujauddin, Syed; Clua-Espuny, Josep Lluis; Reverte-Villarroya, Silvia
Departamento: Infermeria
Autor/es de la URV: Reverté Villarroya, Silvia
Palabras clave: Adults Ag Beta-cell function C-peptide Children Classification Diabetes mellitus Diagnosis Help Mellitus Pilot Predictive ability of c-peptide Prevalence Type 1 diabetes Type 2 diabete Type 2 diabetes Β-cell function
Resumen: Purpose: We aimed to investigate the predictive potential of plasma connecting peptide (C-peptide) in differentiating type 1 diabetes (T1D) from type 2 diabetes (T2D) and to inform evidence-based diabetes classification criteria. Methods: A retrospective review was performed of all the patients with diabetes visiting an outpatient diabetology, endocrinology, general practice and family medicine tertiary health care center between January 2016 and December 2021. Findings: Two hundred twelve individuals with diabetes were included, 85 (44.8%) with T1D and 127 (55.2%) with T2D. Mean (SD) age at diagnosis was 35.9 (15.1) years, and 112 (52.8%) men. Median (interquartile range [IQR]) duration of diabetes was 3.8 (3.0-4.5) years (T1D, 3.9 [3.5-4.6]; T2D, 3.4 [2.4-4.4]; P = 0.001). Body mass index was < 18.5 kg/m2 2 in 5 (2.5%) individuals (T1D, 5; T2D, none), 18.5 to < 25 kg/m2 2 in 57 (28.5%) (T1D, 32; T2D, 25), 25 to < 30 kg/m2 2 in 58 (29%) (T1D, 28; T2D, 30), and > 30 kg/m2 2 in 80 (40.0%) (T1D, 20; T2D, 60). Median (IQR) glycosylated hemoglobin was 7.4% (6.7%-8.5%) (T1D, 8.3% [7.2%-9.9%]; T2D, 7% [6.3%- 7.6%]; P = 0.0001). Median (IQR) C-peptide concentration was 0.59 nmol/L (0.01-1.14 nmol/L) (T1D, 0.01 nmol/L [0.003-0.05 nmol/L]; T2D, 1.03 nmol/L [0.70-1.44 nmol/L]; P = 0.0001). C-peptide concentration of
Áreas temáticas: Ciências biológicas i Ciências biológicas ii Engenharias iv Farmacia General medicine Interdisciplinar Medicina i Medicina ii Medicina iii Pharmacology Pharmacology & pharmacy Pharmacology (medical) Saúde coletiva
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: silvia.reverte@urv.cat
Identificador del autor: 0000-0002-2052-9978
Fecha de alta del registro: 2024-10-05
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Referencia al articulo segun fuente origial: Clinical Therapeutics. 46 (9): 696-701
Referencia de l'ítem segons les normes APA: Iqbal, Sajid; Abu Jayyab, Abdulrahim; Alrashdi, Ayah Mohammad; Shujauddin, Syed; Clua-Espuny, Josep Lluis; Reverte-Villarroya, Silvia (2024). The Predictive Potential of C-Peptide in Differentiating Type 1 Diabetes From Type 2 Diabetes in an Outpatient Population in Abu Dhabi. Clinical Therapeutics, 46(9), 696-701. DOI: 10.1016/j.clinthera.2024.07.002
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2024
Tipo de publicación: Journal Publications
Repositori URV