Autor según el artículo: Iqbal, Sajid; Abu Jayyab, Abdulrahim; Alrashdi, Ayah Mohammad; Shujauddin, Syed; Clua-Espuny, Josep Lluis; Reverte-Villarroya, Silvia
Departamento: Infermeria
Autor/es de la URV: Reverté Villarroya, Silvia / Sajid, Iqbal
Palabras clave: Β-cell function Type 2 diabetes Type 2 diabete Type 1 diabetes Retrospective studies Prevalence Predictive value of tests Predictive ability of c-peptide Pilot Outpatients Middle aged Mellitus Male Humans Help Glycated hemoglobin Female Diagnosis, differential Diagnosis Diabetes mellitus, type 2 Diabetes mellitus, type 1 Diabetes mellitus Classification Children C-peptide Biomarkers Beta-cell function Ag Adults Adult
Resumen: Purpose: We aimed to investigate the predictive potential of plasma connecting peptide (C-peptide) in differentiating type 1 diabetes (T1D) from type 2 diabetes (T2D) and to inform evidence-based diabetes classification criteria. Methods: A retrospective review was performed of all the patients with diabetes visiting an outpatient diabetology, endocrinology, general practice and family medicine tertiary health care center between January 2016 and December 2021. Findings: Two hundred twelve individuals with diabetes were included, 85 (44.8%) with T1D and 127 (55.2%) with T2D. Mean (SD) age at diagnosis was 35.9 (15.1) years, and 112 (52.8%) men. Median (interquartile range [IQR]) duration of diabetes was 3.8 (3.0-4.5) years (T1D, 3.9 [3.5-4.6]; T2D, 3.4 [2.4-4.4]; P = 0.001). Body mass index was < 18.5 kg/m2 2 in 5 (2.5%) individuals (T1D, 5; T2D, none), 18.5 to < 25 kg/m2 2 in 57 (28.5%) (T1D, 32; T2D, 25), 25 to < 30 kg/m2 2 in 58 (29%) (T1D, 28; T2D, 30), and > 30 kg/m2 2 in 80 (40.0%) (T1D, 20; T2D, 60). Median (IQR) glycosylated hemoglobin was 7.4% (6.7%-8.5%) (T1D, 8.3% [7.2%-9.9%]; T2D, 7% [6.3%- 7.6%]; P = 0.0001). Median (IQR) C-peptide concentration was 0.59 nmol/L (0.01-1.14 nmol/L) (T1D, 0.01 nmol/L [0.003-0.05 nmol/L]; T2D, 1.03 nmol/L [0.70-1.44 nmol/L]; P = 0.0001). C-peptide concentration of
Áreas temáticas: Saúde coletiva Pharmacology (medical) Pharmacology & pharmacy Pharmacology Medicina iii Medicina ii Medicina i Interdisciplinar General medicine Farmacia Engenharias iv Ciências biológicas ii Ciências biológicas i
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: silvia.reverte@urv.cat iqbal.sajid@estudiants.urv.cat
Identificador del autor: 0000-0002-2052-9978 0000-0003-0122-6485
Fecha de alta del registro: 2025-01-28
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Clinical Therapeutics. 46 (9): 696-701
Referencia de l'ítem segons les normes APA: Iqbal, Sajid; Abu Jayyab, Abdulrahim; Alrashdi, Ayah Mohammad; Shujauddin, Syed; Clua-Espuny, Josep Lluis; Reverte-Villarroya, Silvia (2024). The Predictive Potential of C-Peptide in Differentiating Type 1 Diabetes From Type 2 Diabetes in an Outpatient Population in Abu Dhabi. Clinical Therapeutics, 46(9), 696-701. DOI: 10.1016/j.clinthera.2024.07.002
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2024
Tipo de publicación: Journal Publications
Repositori URV