Autor según el artículo: Garcia-Arellano A, Ramallal R, Ruiz-Canela M, Salas-Salvadó J, Corella D, Shivappa N, Schröder H, Hébert JR, Ros E, Gómez-Garcia E, Estruch R, Lapetra J, Arós F, Fiol M, Serra-Majem L, Pintó X, Babio N, González JI, Fitó M, Martínez JA, Martínez-González MA, Predimed Investigators

Departamento: Bioquímica i Biotecnologia Medicina i Cirurgia

e-ISSN: 2072-6643

Autor/es de la URV: Babio Sánchez, Nancy Elvira / Basora Gallisa, Josep / Castro Salomó, Antoni / Salas Salvadó, Jorge / Solà Alberich, Rosa Maria

Palabras clave: Randomized controlled trial Prospective study Predimed study Predimed Outcome assessment Olive oil Nut Multicenter study Middle aged Mediterranean diet Male Low fat diet Inflammation Incidence Human High risk population Heart infarction Heart death Food frequency questionnaire Follow up Female Dietary inflammatory index Diet Cerebrovascular accident Cardiovascular risk Cardiovascular disease Assessment of humans Article Aged Adult predimed dietary inflammatory index cardiovascular disease

Resumen: Previous studies have reported an association between a more pro-inflammatory diet profile and various chronic metabolic diseases. The Dietary Inflammatory Index (DII) was used to assess the inflammatory potential of nutrients and foods in the context of a dietary pattern. We prospectively examined the association between the DII and the incidence of cardiovascular disease (CVD: myocardial infarction, stroke or cardiovascular death) in the PREDIMED (Prevención con Dieta Mediterránea) study including 7216 high-risk participants. The DII was computed based on a validated 137-item food frequency questionnaire. Multivariate-adjusted hazard ratios (HR) and 95% confidence intervals of CVD risk were computed across quartiles of the DII where the lowest (most anti-inflammatory) quartile is the referent. Risk increased across the quartiles (i.e., with increasing inflammatory potential): HR(quartile2) = 1.42 (95%CI = 0.97-2.09); HR(quartile3) = 1.85 (1.27-2.71); and HR(quartile4) = 1.73 (1.15-2.60). When fit as continuous the multiple-adjusted hazard ratio for each additional standard deviation of the DII was 1.22 (1.06-1.40). Our results provide direct prospective evidence that a pro-inflammatory diet is associated with a higher risk of cardiovascular clinical events.

Áreas temáticas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 20726643

Direcció de correo del autor: josep.basora@urv.cat nancy.babio@urv.cat rosa.sola@urv.cat jordi.salas@urv.cat antoni.castro@urv.cat josep.basora@urv.cat

Identificador del autor: 0000-0003-3527-5277 0000-0002-8359-235X 0000-0003-2700-7459 0000-0001-5441-6333

Página final: 4138

Fecha de alta del registro: 2023-05-21

Volumen de revista: 7

Versión del articulo depositado: info:eu-repo/semantics/publishedVersion

Enlace a la fuente original: https://www.mdpi.com/2072-6643/7/6/4124

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Nutrients. 7 (6): 4124-4138

Referencia de l'ítem segons les normes APA: Garcia-Arellano A, Ramallal R, Ruiz-Canela M, Salas-Salvadó J, Corella D, Shivappa N, Schröder H, Hébert JR, Ros E, Gómez-Garcia E, Estruch R, Lapetra (2015). Dietary inflammatory index and incidence of cardiovascular disease in the PREDIMED study. Nutrients, 7(6), 4124-4138. DOI: 10.3390/nu7064124

DOI del artículo: 10.3390/nu7064124

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2015

Página inicial: 4124

Tipo de publicación: Journal Publications